Results 231 to 240 of about 420,611 (253)
The Sirtuin1 Activator SRT3025 Down-Regulates Sclerostin and Rescues Ovariectomy-Induced Bone Loss and Biomechanical Deterioration in Female Mice. [PDF]
Endocrinology, 2014 Abstract Estrogen deficiency leads to rapid bone loss and skeletal fragility. Sclerostin, encoded by the sost gene, and a product of the osteocyte, is a negative regulator of bone formation. Blocking sclerostin increases bone mass and strength in animals and humans.
Yankel Gabet +2 more
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In Vivo Biomechanical Changes Associated With Keratoconus Progression [PDF]
Current Eye Research, 2022 Purpose: To assess the biomechanical deterioration arising from keratoconus progression in-vivo. Methods: The preoperative examinations of 32 progressive KC cases that were submitted to corneal cross-linking were evaluated.
Prema Padmanabhan +2 more
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Biomechanical, Structural, and Biochemical Indices of Degenerative and Osteoarthritic Deterioration of Adult Human Articular Cartilage of the Femoral Condyle [PDF]
Osteoarthritis and Cartilage, 2009 To compare the tensile biomechanical properties of age-matched adult human knee articular cartilage exhibiting distinct stages of degenerative or osteoarthritic deterioration and to determine the relationships between tensile properties and biochemical and structural properties hypothesized to underlie functional biomechanical deterioration.Age-matched
Robert Sah, R D Coutts, R L Sah
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Physics of Fluids, 2022
Stent-grafts are bringing new life to aortic dissection patients through thoracic endovascular aortic repair (TEVAR). However, various postoperative complications are threatening the recovery of patients and even require clinical reintervention. The objective of the present study is to reveal the biomechanical mechanism of distal stent-graft-induced ...
Yonghui Qiao, Jianren Fan, Le Mao
exaly +2 more sources
Stent-grafts are bringing new life to aortic dissection patients through thoracic endovascular aortic repair (TEVAR). However, various postoperative complications are threatening the recovery of patients and even require clinical reintervention. The objective of the present study is to reveal the biomechanical mechanism of distal stent-graft-induced ...
Yonghui Qiao, Jianren Fan, Le Mao
exaly +2 more sources
Diabetes Research and Clinical Practice, 2012
To investigate the effect of insulin therapy on biomechanical properties of bone in streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) in rats.A total of 28 male Wistar-Albino rats (12-week-old; 210-300g) were divided into 4 groups (n=7 for each) including control [C; no treatment], sham [Sh; distilled water i.p., for 8 weeks], diabetes [T1DM;
Can Demirel +2 more
exaly +3 more sources
To investigate the effect of insulin therapy on biomechanical properties of bone in streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) in rats.A total of 28 male Wistar-Albino rats (12-week-old; 210-300g) were divided into 4 groups (n=7 for each) including control [C; no treatment], sham [Sh; distilled water i.p., for 8 weeks], diabetes [T1DM;
Can Demirel +2 more
exaly +3 more sources
Aging Male, 2011 The aim of this study was to investigate the effects of the bisphosphonate ibandronate (IBN) in a male osteoporosis animal model.Two studies were performed in 9-month-old orchidectomised (ORX) or sham-operated rats. In prevention study, subcutaneous IBN was administered daily (1 μg/kg) or monthly (28 μg/kg every 28 days) starting on day of surgery for ...
Concepción de la Piedra +2 more
exaly +5 more sources
Bone Biomechanical Property Deterioration Due to Tobacco Smoke Exposure
Calcified Tissue International, 2005Tobacco smoking has been implicated in the development of osteoporosis and early onset of menopause in women smokers. We measured various biomechanical properties of femurs and tibiae obtained from smoke-exposed and control mice to determine cigarette smoke influences on bone mass, structure, and strength.
M P, Akhter, A D, Lund, C G, Gairola
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Tendon Mineralization Is Progressive and Associated With Deterioration of Tendon Biomechanical Properties, and Requires BMP-Smad Signaling in the Mouse Achilles Tendon Injury Model [PDF]
Matrix Biology, 2016 Ectopic tendon mineralization can develop following tendon rupture or trauma surgery. The pathogenesis of ectopic tendon mineralization and its clinical impact have not been fully elucidated yet. In this study, we utilized a mouse Achilles tendon injury model to determine whether ectopic tendon mineralization alters the biomechanical properties of the ...
Masahiro Iwamoto +2 more
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Subtle deterioration in shunted childhood hydrocephalus
Journal of Neurosurgery, 1986✓ Eighteen hydrocephalic children who presented with subtle deterioration when their shunts malfunctioned were studied during shunt revision by means of the pressure-volume index (PVI) technique. Bolus manipulation of cerebrospinal fluid (CSF) was used to determine the PVI and the resistance to the absorption of CSF (Ro).
A, Fried, K, Shapiro
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Enhancing XR Accessibility Through Anthropometrically Diverse Biomechanical Simulation [PDF]
Biomechanical user simulations can complement efforts to enhance XR accessibility by enabling rapid evaluation of alternative design choices across a wider range of user body types and capabilities.
Per Ola Kristensson
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