Results 81 to 90 of about 60,035 (268)

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Biomechanics of stabbing knife attack for trauma surgeons in Korea: a narrative review [PDF]

Journal of Trauma and Injury
The aim of this paper was to review the biomechanics of knife injuries, including those that occur during stabbing rampages. In knife stab attacks, axial force and energy were found to be 1,885 N and 69 J, respectively.
Kun Hwang, Chan Yong Park
doaj   +1 more source

Biomechanical characteristics of the lower extremities during running in male long-distance runners with a history of medial tibial stress syndrome: a case control study

BMC Musculoskeletal Disorders, 2023
Background Medial tibial stress syndrome (MTSS) is a running-related injury of the lower extremities. After returning to competition, there are often recurring episodes of MTSS. Therefore, it is important to prevent the onset and recurrence of MTSS among
Takehiro Ohmi, Junya Aizawa, Kenji Hirohata, Shunsuke Ohji, Sho Mitomo, Toshiyuki Ohara, Kazuyoshi Yagishita   +6 more
doaj   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber‐Unkel, Annette Affolter, Paul Gatenholm, Nicole Rotter, Karen Bieback   +7 more
wiley   +1 more source

Étude de la co-exposition aux contraintes physiques et aux produits chimiques neurotoxiques chez les salariés des Pays de la Loire [PDF]

, 2014
In many working environments, employees face important biomechanical constraints, heavy physical demands and/or shift work. However, epidemiological surveillance has rarely addressed the issue of co-exposure to neurotoxic chemicals and biomechanical risk
A. Nicolas, A. Petit, D. Dupas, P. Harry, Y. Roquelaure   +4 more
core   +2 more sources

Structural Motifs in Soft Fibrous Tissues: Revealing Structure‐Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design

Advanced Healthcare Materials, EarlyView.
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley   +1 more source

Emergent Properties of Tumor Microenvironment in a Real-life Model of Multicell Tumor Spheroids [PDF]

, 2010
Multicellular tumor spheroids are an important {\it in vitro} model of the pre-vascular phase of solid tumors, for sizes well below the diagnostic limit: therefore a biophysical model of spheroids has the ability to shed light on the internal workings ...
A Cornish-Bowden, AM Stein, B Alberts, CD Bortner, D Khaitan, E Gottfried, E Milotti, E Milotti, Edoardo Milotti, EG Flekkøy, F Hirschhaeuser, G Schaller, H Acker, I Wolfram Research, J Alvarez-Pérez, J Friedrich, J O'Rourke, JA Engelberg, JJ Casciari, JM Yuhas, LJ Guibas, LM Sander, M de Berg, MJ Dorie, P Yu, R Bjerkvig, R Chignola, R Chignola, R Chignola, R Chignola, R Chignola, R Chignola, R Venkatasubramanian, RA Dwyer, RM Sutherland, RM Sutherland, Roberto Chignola, RZ Lin, S Walenta, T Nederman, Terence Lee, TS Deisboeck, W Mueller-Klieser, W Mueller-Klieser, W Mueller-Klieser, Y Jiang, Y Kim   +46 more
core   +6 more sources

Impact of Fiber Orientation in Electrospun PLA Scaffolds on Fluid Dynamics in a Custom Microfluidic Device

Advanced Healthcare Materials, EarlyView.
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana, Maria Testa, Chiara Di Marco, Francesco Lopresti, Vincenzo La Carrubba   +4 more
wiley   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Concurrent Biocompatibility and Antimicrobial Functionality of Soft Diamond‐Like Carbon Coating for Healthcare Applications

Advanced Healthcare Materials, EarlyView.
Designing an engineering material that simultaneously promotes the growth of beneficial biological cells while eliminating harmful bacteria is often challenging. However, this study presents a unique carbon coating by manufacturing design capable of achieving both functions, demonstrating strong potential for various applications, including medical ...
Abdul Wasy Zia, Alberto Tuñón‐Molina, Ioannis Anestopoulos, Miguel Martí, Iraklis‐Stavros Panagiotidis, Anam Ijaz, Ángel Serrano‐Aroca, Mihalis I. Panayiotidis, Martin Birkett   +8 more
wiley   +1 more source