Results 101 to 110 of about 512,355 (328)
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs+17 more
wiley +1 more source
Scleral structure and biomechanics
C. Boote+5 more
semanticscholar +1 more source
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley +1 more source
Running Injuries Due to Strike Patterns [PDF]
Running is a very repetitive activity that can lead to surmountable stresses to the body over time that could lead to injury. Running biomechanics can influence the effects that the body will experience.
Rogers, Jamie M
core +1 more source
A Biomechanical Comparison of the Effects of Constant and Cyclic Compression on Fracture Healing in Rabbit Long Bones [PDF]
Manohar M. Panjabi+2 more
openalex +1 more source
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana+4 more
wiley +1 more source
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren+13 more
wiley +1 more source
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Biomimetic, suturable, biodegradable fibrous scaffolds are engineered to mimic the tensile properties of LUT tissue using photocrosslinked 5:5% weight per volume elastin‐like peptide and methacrylated gelatin (5E5G). In vitro, urothelium, smooth muscle, and fibroblast 7 day cytocompatibility is demonstrated.
Renea M. Sturm+18 more
wiley +1 more source