Results 261 to 270 of about 515,259 (376)
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei+11 more
wiley +1 more source
Motor modules are largely unaffected by pathological walking biomechanics: a simulation study. [PDF]
Rahimi Goloujeh M, Allen JL.
europepmc +1 more source
13 Biomechanical Consequences of Sport Shoe Design
Edward C. Frederick
openalex +1 more source
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park+9 more
wiley +1 more source
First metatarsophalangeal joint: Embryology, anatomy and biomechanics. [PDF]
Embaby OM, Elalfy MM.
europepmc +1 more source
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang+8 more
wiley +1 more source
Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu+8 more
wiley +1 more source