Results 71 to 80 of about 2,960,132 (300)

Mid-Infrared Photonic Sensors: Exploring Fundamentals, Advanced Materials, and Cutting-Edge Applications

open access: yesSensors
Mid-infrared (MIR) photonic sensors are revolutionizing optical sensing by enabling precise chemical and biological detection through the interrogation of molecules’ unique vibrational modes.
Muhammad A. Butt   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Biomedical Research, A Tool to Address the Health Issues that Affect African Populations. [PDF]

open access: yes, 2013
Traditionally, biomedical research endeavors in low to middle resources countries have focused on communicable diseases. However, data collected over the past 20 years by the World Health Organization (WHO) show a significant increase in the number of ...
Peprah, Emmanuel, Wonkam, Ambroise
core   +3 more sources

Biomedical mass spectrometry [PDF]

open access: yesAnalytical and Bioanalytical Chemistry, 2012
The 37th Annual Meeting of the Japanese Society for Biomedical Mass Spectrometry (JSBMS) was held on October 25th and 26th, 2012, in Aichi Industry and Labor Center (WINC AICHI), Nagoya, Japan. We aimed for extensive discussions and interdisciplinary cooperation for the researchers in the wide range of areas involved in mass spectrometry; the topics in
Toyofumi, Nakanishi   +2 more
openaire   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

On the proper treatment of pathologies in biomedical ontologies [PDF]

open access: yes, 2005
In previous work on biomedical ontologies we showed how the provision of formal definitions for relations such as is_a and part_of can support new types of auto-mated reasoning about biomedical phenomena.
Kumar, Anand, Smith, Barry
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Biomedical electrode arrangement Patent [PDF]

open access: yes, 1970
Electromedical garment, applying vectorcardiologic type electrodes to human torsos for data recording during physical ...
Roman, J. A.
core   +1 more source

This before That: Causal Precedence in the Biomedical Domain

open access: yes, 2016
Causal precedence between biochemical interactions is crucial in the biomedical domain, because it transforms collections of individual interactions, e.g., bindings and phosphorylations, into the causal mechanisms needed to inform meaningful search and ...
Bell, Dane   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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