Results 161 to 170 of about 19,397,528 (354)

nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation

open access: yesNature Methods, 2020
F. Isensee   +4 more
semanticscholar   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Superparamagnetic nanoparticles for biomedical applications [PDF]

open access: yes
Nanoparticles may provide advanced biomedical research tools based on polymeric or inorganic formulations or a combination of both. They have the potential to be used in many different biological and medical applications as in diagnostic tests assays for
Hofmann, Heinrich   +3 more
core   +2 more sources

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Vision-Language Models for Biomedical Applications

open access: yes
Vision-language models (VLMs) are transforming the landscape of biomedical research and healthcare by enabling the seamless integration and interpretation of complex multimodal data, including medical images and clinical texts.
Thapa, Surendrabikram   +3 more
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

"Novel inorgano-bioorganic nanocomposites for biomedical and engineering applications "Vaikutus"

open access: yes, 2013
The principal objective of the present Project is to establish a long-lasting collaboration, to provide a possibility for transfer of knowledge, to enable exchanges of research personnel, and to create an intercontinental network in the area of hybrid ...
MARQUEZ MF   +9 more
core  

Development of citric acid-based biomaterials for biomedical applications

open access: yes
The development of bioactive materials with controllable preparation is of great significance for biomedical engineering. Citric acid-based biomaterials are one of the few bioactive materials with many advantages such as simple synthesis, controllable ...
Su, M   +7 more
core   +1 more source

Magnetic Nanoparticles: Synthesis, Characterization, and Their Use in Biomedical Field

open access: yesApplied Sciences
In recent years, the use of magnetic nanoparticles (MNPs) in biomedical applications has gained more and more attention. Their unusual properties make them ideal candidates for the advancement of diagnosis, therapy, and imaging applications.
Gabriela Fabiola Stiufiuc   +1 more
doaj   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

open access: yesFEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller   +3 more
wiley   +1 more source

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