Results 81 to 90 of about 1,004,320 (357)
FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source
Journal of Regional Medical Campuses, 2018 Biomedical engineering is the fastest growing engineering field in the United States, preparing a generation of skilled problem-solvers who, together with healthcare professionals, drive the momentum of novel technologies for prevention, detection ...
Raj Raghavendra Rao +3 more
doaj +1 more source
Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells
FEBS Open Bio, EarlyView.Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki +5 more
wiley +1 more source
Multi-Structural Signal Recovery for Biomedical Compressive Sensing [PDF]
arXiv, 2013 Compressive sensing has shown significant promise in biomedical fields. It reconstructs a signal from sub-Nyquist random linear measurements. Classical methods only exploit the sparsity in one domain. A lot of biomedical signals have additional structures, such as multi-sparsity in different domains, piecewise smoothness, low rank, etc.
arxiv
Multi-Perspective Semantic Information Retrieval in the Biomedical Domain [PDF]
arXiv, 2020 Information Retrieval (IR) is the task of obtaining pieces of data (such as documents) that are relevant to a particular query or need from a large repository of information. IR is a valuable component of several downstream Natural Language Processing (NLP) tasks.
arxiv
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
Sputtering of Electrospun Polymer-Based Nanofibers for Biomedical Applications: A Perspective
Nanomaterials, 2019 Electrospinning has gained wide attention recently in biomedical applications. Electrospun biocompatible scaffolds are well-known for biomedical applications such as drug delivery, wound dressing, and tissue engineering applications.
Hana Kadavil +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel +4 more
wiley +1 more source
Biomedical Evidence Generation Engine [PDF]
arXiv, 2019 With the rapid development of precision medicine, a large amount of health data (such as electronic health records, gene sequencing, medical images, etc.) has been produced. It encourages more and more interest in data-driven insight discovery from these data. It is a reasonable way to verify the derived insights in biomedical literature.
arxiv