Results 81 to 90 of about 3,433,768 (395)

Biomedical Engineering And Its Potential For Employment in Indonesia

International Journal of Technology, 2014
Indonesia, as cited by the World Health Organization (WHO), is still listed as one of the countries who spend less of its GDP on health services, despite the urgent need to overcome the high rate of medical cases in several diseases.
Maria Elfani, Narendra Kurnia Putra
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Problem-Oriented Modelling for Biomedical Engineering Systems

Applied Sciences, 2022
Technical system (TS) models are widely used for setting and solving problems for the improvement of biomedical engineering systems beyond simple parameter optimisation. They mostly focus on system elements, the change or replacement of which can provide
Ivan Kernytskyy, Larysa Hlinenko, Yevheniia Yakovenko, Orest Horbay, Eugeniusz Koda, Konstantin Rusakov, Volodymyr Yankiv, Ruslan Humenuyk, Pavlo Polyansky, Serhii Berezovetskyi, Marek Kalenik, Olga Szlachetka   +11 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Surface-Modified Nanocellulose for Application in Biomedical Engineering and Nanomedicine: A Review

International Journal of Nanomedicine, 2020
Presently, a plenty of concerns related to the environment are due to the overuse of petroleum-based chemicals and products; the synthesis of functional materials, starting from the natural sources, is the current trend in research.
S. Tortorella, Veronica Vetri Buratti, M. Maturi, L. Sambri, M. Comes Franchini, E. Locatelli   +5 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

A simulation study on the effects of neuronal ensemble properties on decoding algorithms for intracortical brain-machine interfaces [PDF]

, 2018
Background: Intracortical brain-machine interfaces (BMIs) harness movement information by sensing neuronal activities using chronic microelectrode implants to restore lost functions to patients with paralysis.
AP Georgopoulos, B Amirikian, Bongsoo Lee, C Chestek, CE Bouton, DM Taylor, E Salinas, G Santhanam, IH Stevenson, JE O’Doherty, Jeong-woo Sohn, JF Kalaska, JH Zar, JL Collinger, JM Carmena, JP Cunningham, JP Donoghue, LF Nicolas-Alonso, LR Hochberg, LR Hochberg, M Velliste, MA Lebedev, MD Serruya, Min-Ki Kim, PH Franses, PH Franses, RE Kass, S Koyama, S Musallam, S Waldert, SM Chase, SP Kim, SP Kim, Sung-Phil Kim, T Aflalo, V Gilja, W Shain, W Wu, X Zheng   +38 more
core   +2 more sources

A Survey of Tactile-Sensing Systems and Their Applications in Biomedical Engineering

Advances in Materials Science and Engineering, 2020
Over the past few decades, tactile sensors have become an emerging field of research in both academia and industry. Recent advances have demonstrated application of tactile sensors in the area of biomedical engineering and opened up new opportunities for
Yousef Al-Handarish, O. Omisore, Tobore Igbe, Shipeng Han, Hui Li, Wenjing Du, Jinjie Zhang, Lei Wang   +7 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

BIMS: Biomedical Information Management System [PDF]

arXiv, 2013
In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research projects. The main goal is to facilitate the clinicians' job in data entry, and researcher's tasks in data management, in
arxiv