Results 41 to 50 of about 137,241 (263)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Medical Device Safety Management Using Cybersecurity Risk Analysis

IEEE Access, 2020
Hospital biomedical engineering teams are responsible for establishing and regulating medical equipment management programs (MEMPs); these programs ensure the safety and reliability of medical devices.
Dong-Won Kim, Jin-Young Choi, Keun-Hee Han   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Augmented reality-based feedback for technician-in-the-loop C-arm repositioning

Healthcare Technology Letters, 2018
Interventional C-arm imaging is crucial to percutaneous orthopedic procedures as it enables the surgeon to monitor the progress of surgery on the anatomy level.
Mathias Unberath, Javad Fotouhi, Javad Fotouhi, Jonas Hajek, Andreas Maier, Greg Osgood, Russell Taylor, Mehran Armand, Nassir Navab   +8 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Assessment of the operational status of medical equipment in public hospitals in the Amhara region, Ethiopia: a sub-national study

Discover Health Systems
Background The functionality of medical equipment is critical for effective clinical service delivery. Despite the growing use of advanced medical equipment, the majority of hospitals in the Amhara region face difficulties, such as inadequate maintenance
Negese Sewagegn, Tadese Tilahun, Gizew Dessie, Belay Bezabih   +3 more
doaj   +1 more source

Profiling the propagation of error from PPG to HRV features in a wearable physiological-monitoring device

Healthcare Technology Letters, 2018
Wearable physiological monitors are becoming increasingly commonplace in the consumer domain, but in literature there exists no substantive studies of their performance when measuring the physiology of ambulatory patients.
Davide Morelli, Leonardo Bartoloni, Michele Colombo, David Plans, David A. Clifton   +4 more
doaj   +1 more source

Imaging of fluorescent polymer dots in relation to channels and immune cells in the lymphatic system

Materials Today Bio, 2022
Polymer dots (Pdots) have been applied to imaging lymph nodes (LNs) and lymphatic vessels (LVs) in living mice and rats. However, the mechanism of absorption, distribution, metabolism, and excretion of Pdots in LNs and LVs is still unclear.
Yufan Zhang, Juxiang Zhang, Xiaowei Li, Jingru Li, Shuting Lu, Yuqiao Li, Panting Ren, Chunfu Zhang, Liqin Xiong   +8 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source