Results 51 to 60 of about 860,856 (301)

Fusion of various optimisation based feature smoothing methods for wearable and non‐invasive blood glucose estimation

IET Systems Biology, 2023
The traditional blood glucose estimation method requires to take the invasive measurements several times a day. Therefore, it has a high infection risk and the users are suffered from the pain. Moreover, the long term consumable cost is high.
Yiting Wei, Bingo Wing‐Kuen Ling, Danni Chen, Yuheng Dai, Qing Liu   +4 more
doaj   +1 more source

Accuracy Verification of an Anatomical Model Manufactured Using Low-Cost Additive Production

Applied Sciences, 2021
The paper deals with the separation of the third cervical vertebra using the software VGStudio MAX, Mimics, and inVesalius. During the separation, various parameters of the threshold were used to determine the effect. The comparison of models from Mimics
Teodor Tóth, Patrik Varga, Branko Štefanovič, Lucia Bednarčíková, Marek Schnitzer, Radovan Hudák, Jozef Živčák   +6 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Development and application of radar reflectometer using micro to infrared waves

Advances in Physics: X, 2018
Progress in microwave and millimeter-wave technologies has made possible advanced diagnostics for application to various fields, including radio astronomy, alien substance detection, plasma diagnostics, airborne and space-borne imaging radars called as ...
A. Mase, Y. Kogi, D. Kuwahara, Y. Nagayama, N. Ito, T. Maruyama, H. Ikezi, X. Wang, M. Inutake, T. Tokuzawa, J. Kohagura, M. Yoshikawa, S. Shinohara, A. Suzuki, F. Sakai, M. Yamashika, B. J. Tobias, C. Muscatello, X. Ren, M. Chen, C. W. Domier, N. C. Luhmann   +21 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Calibration‐free structured‐light‐based 3D scanning system in laparoscope for robotic surgery

Healthcare Technology Letters
Accurate 3D shape measurement is crucial for surgical support and alignment in robotic surgery systems. Stereo cameras in laparoscopes offer a potential solution; however, their accuracy in stereo image matching diminishes when the target image has few ...
Ryo Furukawa, Elvis Chen, Ryusuke Sagawa, Shiro Oka, Hiroshi Kawasaki   +4 more
doaj   +1 more source

Noninvasive depth estimation using tissue optical properties and a dual-wavelength fluorescent molecular probe in vivo [PDF]

, 2017
Translation of fluorescence imaging using molecularly targeted imaging agents for real-time assessment of surgical margins in the operating room requires a fast and reliable method to predict tumor depth from planar optical imaging.
Achilefu, Samuel, Lam, Jesse, Maji, Dolonchampa, Miller, Jessica P, Tromberg, Bruce J   +4 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Proof of Concept for an Intracochlear Acoustic Receiver for Use in Acute Large Animal Experiments

Sensors, 2018
(1) Background: The measurement of intracochlear sound pressure (ICSP) is relevant to obtain better understanding of the biomechanics of hearing. The goal of this work was a proof of concept of a partially implantable intracochlear acoustic receiver ...
Flurin Pfiffner, Lukas Prochazka, Ivo Dobrev, Karina Klein, Patrizia Sulser, Dominik Péus, Jae Hoon Sim, Adrian Dalbert, Christof Röösli, Dominik Obrist, Alexander Huber   +10 more
doaj   +1 more source

Comparison of Classification Algorithms for Detecting Patient Posture in Expandable Tumor Prostheses

Advances in Electrical and Computer Engineering, 2020
Autonomous tumor prostheses are extended without the need of a clinic and of a medical supervision. It is necessary to make sure that the patient is not standing before extending these prostheses. This study aims to determine the posture of the patient
KOCAOGLU, S., AKDOGAN, E.
doaj   +1 more source