Results 71 to 80 of about 866,592 (283)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Widefield multifrequency fluorescence lifetime imaging using a two-tap complementary metal-oxide semiconductor camera with lateral electric field charge modulators. [PDF]
, 2019 Widefield frequency-domain fluorescence lifetime imaging microscopy (FD-FLIM) measures the fluorescence lifetime of entire images in a fast and efficient manner.
Chen, Hongtao +5 more
core
Respiration monitoring by combining EMG and bioimpedance measurements
, 2018 Full abstract in the ...
Kusche, Roman, Ryschka, Martin
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Drop Measurement System for Biomedical Application
IEEE Transactions on Instrumentation and Measurement, 2015 This paper describes the realization of a sensor capable of measuring the volume of a drop in free fall. The sensor realized is made of a simple low-cost red laser and a photodiode and optics to focus the beam on the light sensor. In this way, when the drop is falling down, it is possible to estimate its volume from the signal generated on the ...
NORGIA, MICHELE +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Secured remote health monitoring system
Healthcare Technology Letters, 2017 Wireless medical sensor network is used in healthcare applications that have the collections of biosensors connected to a human body or emergency care unit to monitor the patient's physiological vital status.
Duraisamy Sathya +1 more
doaj +1 more source
The Statistical Analysis of Behavioural Latency Measures [PDF]
, 1997 This article concerns two important problems with the statistical analysis of behavioural latency measures: they typically have severely skewed distributions, and are often censored (truncated).
Budaev, Dr. Sergey
core
Electroolfactogram (EOG) Recording in the Mouse Main Olfactory Epithelium [PDF]
, 2013 Olfactory sensory neurons in the main olfactory epithelium (MOE) are responsible for detecting odorants and EOG recording is a reliable approach to analyze the peripheral olfactory function.
Chen, Xuanmao +2 more
core +2 more sources