Results 71 to 80 of about 860,856 (301)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Accuracy assessment of Tri-plane B-mode ultrasound for non-invasive 3D kinematic analysis of knee joints [PDF]

open access: yes, 2016
BACKGROUND Currently the clinical standard for measuring the motion of the bones in knee joints with sufficient precision involves implanting tantalum beads into the bones.
Lambert, Andrew   +4 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Statistical Analysis of Behavioural Latency Measures [PDF]

open access: yes, 1997
This article concerns two important problems with the statistical analysis of behavioural latency measures: they typically have severely skewed distributions, and are often censored (truncated).
Budaev, Dr. Sergey
core  

Respiration monitoring by combining EMG and bioimpedance measurements

open access: yes, 2018
Full abstract in the ...
Kusche, Roman, Ryschka, Martin
core   +1 more source

Drop Measurement System for Biomedical Application

open access: yesIEEE Transactions on Instrumentation and Measurement, 2015
This paper describes the realization of a sensor capable of measuring the volume of a drop in free fall. The sensor realized is made of a simple low-cost red laser and a photodiode and optics to focus the beam on the light sensor. In this way, when the drop is falling down, it is possible to estimate its volume from the signal generated on the ...
NORGIA, MICHELE   +3 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Secured remote health monitoring system

open access: yesHealthcare Technology Letters, 2017
Wireless medical sensor network is used in healthcare applications that have the collections of biosensors connected to a human body or emergency care unit to monitor the patient's physiological vital status.
Duraisamy Sathya   +1 more
doaj   +1 more source

A FLEXIBLE MEASURE OF CONTEXTUAL SIMILARITY FOR BIOMEDICAL TERMS [PDF]

open access: yesBiocomputing 2005, 2004
We present a measure of contextual similarity for biomedical terms. The contextual features need to be explored, because newly coined terms are not explicitly described and efficiently stored in biomedical ontologies and their inner features (e.g. morphologic or orthographic) do not always provide sufficient information about the properties of the ...
Spasić, I., Ananiadou, S.
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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