Results 81 to 90 of about 866,592 (283)

A FLEXIBLE MEASURE OF CONTEXTUAL SIMILARITY FOR BIOMEDICAL TERMS [PDF]

Biocomputing 2005, 2004
We present a measure of contextual similarity for biomedical terms. The contextual features need to be explored, because newly coined terms are not explicitly described and efficiently stored in biomedical ontologies and their inner features (e.g. morphologic or orthographic) do not always provide sufficient information about the properties of the ...
Spasić, I., Ananiadou, S.
openaire   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Development of measurement technique of living body flexibility by indentation test using concentrated mass model

Nihon Kikai Gakkai ronbunshu, 2015
Palpation is an important diagnostic technique in medicine. However, it is subjective, and successful diagnosis depends on the skill and experience of the doctor.
Satoshi ISHIKAWA, Shinya KIJIMOTO, Yosuke KOBA, Keisuke FUJIHARA   +3 more
doaj   +1 more source

Noninvasive depth estimation using tissue optical properties and a dual-wavelength fluorescent molecular probe in vivo [PDF]

, 2017
Translation of fluorescence imaging using molecularly targeted imaging agents for real-time assessment of surgical margins in the operating room requires a fast and reliable method to predict tumor depth from planar optical imaging.
Achilefu, Samuel, Lam, Jesse, Maji, Dolonchampa, Miller, Jessica P, Tromberg, Bruce J   +4 more
core   +2 more sources

Pressure Measurement at Biomedical Interfaces

, 2011
The science of pressure measurement is mature with many available pressure measurement technologies some of which have their origins dating back to steam power and the industrial revolution. Along with temperature, the use of pressure as a general physiological parameter is well established and it may be accurately and reliably determined for a wide ...
Casey, Vincent, Grace, Pierce, Clarke-Moloney, Mary   +2 more
openaire   +3 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Contactless and short‐range vital signs detection with doppler radar millimetre‐wave (76–81 GHz) sensing firmware

Healthcare Technology Letters
Vital signs such as heart rate (HR) and respiration rate (RR) are essential physiological parameters that are routinely used to monitor human health and bodily functions.
Pi‐Yun Chen, Hsu‐Yung Lin, Zi‐Heng Zhong, Neng‐Sheng Pai, Chien‐Ming Li, Chia‐Hung Lin   +5 more
doaj   +1 more source

Data mining process for predicting diabetes mellitus based model about other chronic diseases: a case study of the northwestern part of Nigeria

Healthcare Technology Letters, 2019
To predict diabetes mellitus model data mining (DM) based approaches on the dataset collected from the seven northwestern states of Nigeria. Data were collected from both primary and secondary sources through questionnaires and verbal interviews from ...
Muhammad Musa Uba, Ren Jiadong, Muhammad Noman Sohail, Muhammad Irshad, Muhammad Irshad, Kaifei Yu   +5 more
doaj   +1 more source

CNN-Based Projected Gradient Descent for Consistent Image Reconstruction

, 2017
We present a new method for image reconstruction which replaces the projector in a projected gradient descent (PGD) with a convolutional neural network (CNN).
Gupta, Harshit, Jin, Kyong Hwan, McCann, Michael T., Nguyen, Ha Q., Unser, Michael   +4 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source