Results 51 to 60 of about 682,032 (261)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Instrumented Analysis of the Sit-to-Stand Movement for Geriatric Screening: A Systematic Review

open access: yesBioengineering, 2020
The Sit-to-Stand (STS) is a widely used test of physical function to screen older people at risk of falls and frailty and is also one of the most important components of standard screening for sarcopenia.
Brajesh Shukla   +4 more
doaj   +1 more source

Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing

open access: yesIEEE Access, 2022
Home sleep apnea testing (HSAT) without electroencephalography (EEG) recording is increasingly used as an alternative to in-laboratory polysomnography for the diagnosis of obstructive sleep apnea (OSA). However, without EEG, electrooculography (EOG), and
Laura Kalevo   +9 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Vital Sign Monitoring Using FMCW Radar in Various Sleeping Scenarios

open access: yesSensors, 2020
Remote monitoring of vital signs for studying sleep is a user-friendly alternative to monitoring with sensors attached to the skin. For instance, remote monitoring can allow unconstrained movement during sleep, whereas detectors requiring a physical ...
Emmi Turppa   +3 more
doaj   +1 more source

Structural Engineering for High‐Performance Flexible and Stretchable Strain Sensors

open access: yesAdvanced Intelligent Systems, 2021
Structural engineering is proved to be effective in improving both measurement sensitivity and range for flexible and stretchable strain sensors. Herein, the latest advancements in structural engineering strategies are summarized for the improvement of ...
Xin Huang, Zhouping Yin, Hao Wu
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Novel Coronavirus Cough Database: NoCoCoDa

open access: yesIEEE Access, 2020
The current pandemic associated with the novel coronavirus (COVID-19) presents a new area of research with its own set of challenges. Creating unobtrusive remote monitoring tools for medical professionals that may aid in diagnosis, monitoring and contact
Madison Cohen-McFarlane   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Smart Textile Systems for Loneliness Monitoring in Older People Care: A Review of Sensing and Design Innovations

open access: yesAdvanced Electronic Materials
Loneliness is a critical issue among older people and poses a significant risk factor for various physical and mental health conditions. While recent wearable technologies can monitor behavioral and physiological changes associated with loneliness ...
Yi Zhou   +12 more
doaj   +1 more source

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