Results 81 to 90 of about 678,535 (278)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
IEEE AccessClinical diagnoses of mental health disorders are often subjective, leading to misdiagnoses and underdiagnoses. AI-based diagnostic tools have emerged as promising approaches for improving diagnostic accuracy. However, effective models with interpretable
Segun Olatinwo, Rita Orji
doaj +1 more source
Learning from medical data streams: an introduction [PDF]
, 2011 Clinical practice and research are facing a new challenge created by the rapid growth of health information science and technology, and the complexity and volume of biomedical data.
Gaber, M. +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
User's manual for SESL-EMU biomedical monitoring and computations system Final report [PDF]
Biomedical monitoring and computation ...
core +1 more source
Biomedical Sensors Based Monitoring System
, 2018 Electricity-operated durable medical equipment (DME), such as ventilators, dialysis machines, and patient monitoring devices, are life-supporting machines used extensively by patients at home. While convenient and economical, at-home use of DME is susceptible to power outages, especially the ones caused by natural disasters that often occur in large ...
openaire +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Optical-electronic monitoring system of biomedical indicators
Фізика і хімія твердого тіла, 2020 The work is devoted to the development of medical systems for monitoring biomedical indicators. The problem of developing a universal hardware software-controlled control system for the diagnosis of biological objects is solved. The main requirements for
G.I. Barylo +3 more
doaj +1 more source