Results 141 to 150 of about 764,785 (295)

WormBase 2007 [PDF]

, 2008
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence
A. Petcherski, A. Rogers, Ashburner, C. Bastiani, C. Nakamura, D. Blasiar, D. Wang, Deplancke, E. M. Schwarz, G. Schindelman, G. Williams, H.-M. Muller, Hillier, Husson, I. Antoshechkin, J. Chan, J. Fernandes, J. Spieth, K. Van Auken, K. Yook, Kirienko, L. D. Stein, Li, Li, M. A. Tuli, M. Han, Matera, Meyer, M  ller, O'Brien, P. Canaran, P. Davis, P. Ozersky, P. W. Sternberg, Potter, R. Durbin, R. Kishore, R. Lee, Ruby, S. McKay, T. Bieri, T. J. Fiedler, T. W. Harris, Tatusov, W. J. Chen, W. Spooner, Wachi, Walhout, X. Wang, Zemann, Zhang, Zhong   +51 more
core   +3 more sources

Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies

Journal of Extracellular Vesicles, 2015
The large diversity and volume of extracellular RNA (exRNA) data that will form the basis of the exRNA Atlas generated by the Extracellular RNA Communication Consortium pose a substantial data integration challenge.
S. L. Subramanian, R. Kitchen, Roger P. Alexander, B. Carter, Kei-Hoi Cheung, L. Laurent, Alexander R. Pico, L. Roberts, M. Roth, J. Rozowsky, A. Su, M. Gerstein, A. Milosavljevic   +12 more
semanticscholar   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

The development of non-coding RNA ontology [PDF]

, 2016
Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data ...
Blake, Judith, de Silva, Nisansa, Dou, Deijing, Eilbeck, Karen, Huan, Jun, Huang, Jingshan, Huang, Weili, Jiang, Guoqian, Kasukurthi, Mohan Vamsi, Lin, Yu, Natale, Darren, Ruttenberg, Alan, Smith, Barry, Strachan, Harrison, Wu, Bin, Zimmermann, Michael   +15 more
core   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

An Overview of Biomedical Ontologies for Pandemics and Infectious Diseases Representation. [PDF]

Procedia Comput Sci, 2021
Bayoudhi L, Sassi N, Jaziri W.
europepmc   +1 more source

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

Advanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu, Kexing Li, Yuge Wang, Hongyu Li, Hongyu Zhao   +4 more
wiley   +1 more source

A visual representation of part-whole relationships in BFO-conformant ontologies [PDF]

, 2017
In the visual representation of ontologies, in particular of part-whole relationships, it is customary to use graph theory as the representational background.
de Oliveira, Jose M. Parente, Smith, Barry   +1 more
core  

Merging Biomedical Ontologies with BioSTransformers

Ontologies play a key role in representing and structuring domain knowledge. In the biomedical domain, the need for this type of representation is crucial for structuring, coding, and retrieving data. However, available ontologies do not encompass all the relevant concepts and relationships.
Menad, Safaa, Abdeddaïm, Saïd, Soualmia, Lina F.   +2 more
openaire   +2 more sources

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source