Results 41 to 50 of about 10,697,158 (290)

Scholarly communication and open access : research communities and their publishing patterns [New Trends in Scholarly Communication : how do Authors of different research communities consider OA?] [PDF]

open access: yes, 2005
At the time of the Budapest Declaration, self-archiving supporters looked like a revolutionary, "anti-commercial publishers" movement. Today, after some years debate (and technological innovation in research and scientific e-publishing), antagonist ...
Comba, Valentina, Vignocchi, Marialaura
core   +1 more source

Pitfalls of Using Multinomial Regression Analysis to Identify Class-Structure-Relevant Variables in Biomedical Data Sets: Why a Mixture of Experts (MOE) Approach Is Better

open access: yes, 2023
Recent advances in mathematical modeling and artificial intelligence have challenged the use of traditional regression analysis in biomedical research. This study examined artificial data sets and biomedical data sets from cancer research using binomial ...
Jörn Lötsch, Alfred Ultsch
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The landscape of biomedical research progress, challenges and prospects in Saudi Arabia-A systematic review

open access: yesDigital Health, 2023
Introduction The main objective of this review was to synthesize the progress, challenges and prospects of biomedical research in Saudi Arabia in order to provide a holistic view to all stakeholders, such as policy makers, decision makers, and local ...
Mohy Uddin, Naif Khalaf Alharbi
doaj   +1 more source

AI-Based Biomedical Signal Processing

open access: yes
Motivated by the numerous studies working towards innovative processing of biomedical signals, especially exploiting Artificial Intelligence (AI)-based methodologies, this Special Issue was proposed in 2022 [...
Aurora Saibene, Agnese Sbrollini
core   +1 more source

The Variable Fee Structure for Eagle Editions: The Scholarly Publishing Services of the University of North Texas Libraries [PDF]

open access: yes, 2015
Poster presented at the 2015 Library Publishing Forum. This poster provides an overview of a recently launched scholarly publishing service at the University of North ...
Hawkins, Kevin S.
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Using the Gene Ontology to Annotate Biomedical Journal Articles [PDF]

open access: yes, 2009
We are creating a gold-standard corpus of manually annotated full-text biomedical journal articles toward natural-language-processing applications. Central to this is our use of entire ontologies of the Open Biomedical Ontologies initiative as well as ...
Michael Bada, Lawrence Hunter
core   +1 more source

Home - About - Disclaimer - Privacy