Results 51 to 60 of about 2,344,465 (331)

Pre-clinical biomedical research

Revista Cubana de Estomatología, 2015
Introduction: a historical analysis would reveal that the use of animals as test subjects has been both effective and essential. Such a practice has served both to save lives and to answer a variety of biomedical questions.
Denia Morales Navarro
doaj  

Informed Consent in Biomedical Research

Computational and Structural Biotechnology Journal, 2019
Informed consent is the result of tumultuous events in both the clinical and research arenas over the last 100 years. Throughout this time, the notion of informed consent has shifted tremendously, both due to advances in medicine, as well as the type of ...
Fida K. Dankar, Marton Gergely, Samar K. Dankar   +2 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Proposing Disciplinary Charter of Research Misconduct: a Qualitative Study [PDF]

Strides in Development of Medical Education, 2010
Background & Objective: The number of research misconduct cases seems to be increasing so the need for developing a disciplinary charter of research misconduct is felt more than ever This study was aimed to propose and develop a charter to determine ...
Nouzar Nakhaee, Hamid Najafipour, Aliakbar Rohani, Shahrokh Raftari, Mina Mobasher, Fatemeh Hasani   +5 more
doaj  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Organs-on-Chips: Revolutionizing Biomedical Research

Biophysica
Organs-on-Chips (OoC) technology has begun to be considered a pragmatic tool for drug evaluation, offering researchers an opportunity to move beyond the less physiologically relevant animal models.
Ankit Monga, Khush Jain, Harvinder Popli, Prashik Telgote, Ginpreet Kaur, Fariah Rizwani, Ritu Chauhan, Damandeep Kaur, Abhishek Chauhan, Hardeep Singh Tuli   +9 more
doaj   +1 more source

BMC Biomedical Engineering: a home for all biomedical engineering research

BMC Biomedical Engineering, 2019
This editorial accompanies the launch of BMC Biomedical Engineering, a new open access, peer-reviewed journal within the BMC series, which seeks to publish articles on all aspects of biomedical engineering. As one of the first engineering journals within
Alexandros Houssein, Alan Kawarai Lefor, Antonio Veloso, Zhi Yang, Jong Chul Ye, Dimitrios I. Zeugolis, Sang Yup Lee   +6 more
doaj   +1 more source

Nanotechnology for Environmental and Biomedical Research [PDF]

Nanomaterials, 2020
Given the high production and broad feasibility of nanomaterials, the application of nanotechnology includes the use of engineered nanomaterials (ENMs) to clean-up polluted media such as soils, water, air, groundwater and wastewaters, and is known as nanoremediation [...]
openaire   +3 more sources

Biomedical Research Involving Prisoners: Ethical Values and Legal Regulation [PDF]

, 2007
Until the early 1970\u27s, approximately 90% of all pharmaceutical research was conducted on prisoners, who were also subjected to biochemical research, including studies involving dioxin and chemical warfare agents.
Gostin, Lawrence O.
core   +1 more source

Figure mining for biomedical research [PDF]

, 2009
Motivation: Figures from biomedical articles contain valuable information difficult to reach without specialized tools. Currently, there is no search engine that can retrieve specific figure types.
Iossifov, I., Rodriguez-Esteban, R.
core   +1 more source