Results 51 to 60 of about 2,451,565 (299)

Proposing Disciplinary Charter of Research Misconduct: a Qualitative Study [PDF]

open access: yesStrides in Development of Medical Education, 2010
Background & Objective: The number of research misconduct cases seems to be increasing so the need for developing a disciplinary charter of research misconduct is felt more than ever This study was aimed to propose and develop a charter to determine ...
Nouzar Nakhaee   +5 more
doaj  

Informed Consent in Biomedical Research

open access: yesComputational and Structural Biotechnology Journal, 2019
Informed consent is the result of tumultuous events in both the clinical and research arenas over the last 100 years. Throughout this time, the notion of informed consent has shifted tremendously, both due to advances in medicine, as well as the type of ...
Fida K. Dankar   +2 more
doaj   +1 more source

Appropriation of value in Biomedical research outcome at Public Research Organisations [PDF]

open access: yes, 2008
Transactions on biomedical research outcomes bring into play strategies that are determined by leveraging resources into quasi-markets and on options based on expectations.
Groen, Aard, Kensah, David
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Organs-on-Chips: Revolutionizing Biomedical Research

open access: yesBiophysica
Organs-on-Chips (OoC) technology has begun to be considered a pragmatic tool for drug evaluation, offering researchers an opportunity to move beyond the less physiologically relevant animal models.
Ankit Monga   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

BMC Biomedical Engineering: a home for all biomedical engineering research

open access: yesBMC Biomedical Engineering, 2019
This editorial accompanies the launch of BMC Biomedical Engineering, a new open access, peer-reviewed journal within the BMC series, which seeks to publish articles on all aspects of biomedical engineering. As one of the first engineering journals within
Alexandros Houssein   +6 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Bridges to the Baccalaureate Program at J. Sargeant Reynolds Community College and Virginia Commonwealth University [PDF]

open access: yes, 2001
This paper describes a research apprenticeship to encourage and to inspire minority students to major in disciplines that lead to careers in biomedical ...
Neely-Fisher, D.
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy