Results 91 to 100 of about 5,682,413 (331)
Majalah Kedokteran AndalasTujuan: Penelitian ini untuk mengetahui sensitifitas kotrimoksazol terhadap bakteri penyebab Infeksi Saluran Kemih (ISK) pada pasien diabetes melitus tipe 2.
Shafira Kurnia Warianti +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Novel foods: a risk profile for the house cricket (Acheta domesticus)
EFSA Journal, 2018 Novel foods could represent a sustainable alternative to traditional farming and conventional foodstuffs. Starting in 2018, Regulation (EU) 2283/2015 entered into force, laying down provisions for the approval of novel foods in Europe, including insects.
SLU, Swedish University of Agricultural Sciences +6 more
doaj +1 more source
The Virtual Health Sciences Library of the Balearic Islands: A regional project for libraries cooperation. [PDF]
, 2010 Virtual Health Sciences Library of the Balearic Islands (Bibliosalut) is a regional project carried out in collaboration with the Regional Ministry of Health and Consumer Protection and the Health Service of the Balearic Islands (Ib-salut), through the ...
Costa-Marín, Maria +4 more
core
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Una introducción a la mecanobiología computacional An introduction to computation mechanobiology
Revista Cubana de Investigaciones Biomédicas, 2011 La mecanobiología estudia el comportamiento de células, tejidos y órganos bajo los efectos de la bioquímica, la biología celular y los estímulos externos, como las cargas mecánicas. Esta involucra el desarrollo de modelos y la realización de experimentos
Nancy Landinez Parra +2 more
doaj
Bridging the gap between social tagging and semantic annotation: E.D. the Entity Describer [PDF]
, 2007 Semantic annotation enables the development of efficient computational methods for analyzing and interacting with information, thus maximizing its value.
Benjamin M. Good +2 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
DNA-encoded libraries – an efficient small molecule discovery technology for the biomedical sciences
Biological chemistry, 2018 DNA-encoded compound libraries are a highly attractive technology for the discovery of small molecule protein ligands. These compound collections consist of small molecules covalently connected to individual DNA sequences carrying readable information ...
Verena B. K. Kunig +3 more
semanticscholar +1 more source