Results 61 to 70 of about 5,682,413 (331)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Core Curriculum in the Biological and Biomedical Sciences for Dentistry.

European journal of dental education, 2020
INTRODUCTION The biomedical sciences (BMS) are a central part of the dental curriculum that underpins teaching and clinical practice in all areas of dentistry. Although some specialist groups have proposed curricula in their particular topic areas, there
J. Bennett, J. Beeley, P. Anderson, Louise A. Belfield, H. Brand, A. Didilescu, D. Dymock, Y. Guven, M. Hector, P. Holbrook, J. Jayasinghe, Jeff O'Sullivan, M. Riggio, V. Roger-Leroi, B. Scheven, A. Sloan, K. Vandamme, M. Manzanares   +17 more
semanticscholar   +1 more source

Spectrum of topics for world congresses and other activities of the International Society for Physical and Rehabilitation Medicine (ISPRM) : a first proposal [PDF]

, 2013
Background: One of the objectives of the International Society for Physical and Rehabilitation Medicine is to improve the continuity of World Congresses.
Fialka-Moser, Veronika, Gutenbrunner, Christoph, Guzman, Manuel, Imamura, Marta, Li, Jianan, Li, Leonard SW, Stucki, Gerold, Vanderstraeten, Guy, Ward, Anthony B   +8 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Singapore's biomedical sciences landscape [PDF]

Journal of Commercial Biotechnology, 2007
Singapore's vision is to be the Biopolis of Asia, a leading international biomedical sciences cluster advancing human health, through the pursuit of excellence in research and development, manufacturing and healthcare delivery. To achieve this, Singapore has built up world-class capabilities across the entire value chain from drug discovery ...
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The importance of measuring skin resistance for electrical nociceptive stimulation in standing horses [PDF]

, 2017
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Veterinary Surgery and Anaesthesiology Faculty of Veterinary Medicine and Animal Science UNESP – Univ.
Crosignani, N, Gozalo-Marcilla, M, Luna, S P L, Pelligand, L, Puoli Filho, J N P, Taylor, P M   +5 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Controlled vocabularies in bioinformatics: A case study in the Gene Ontology [PDF]

, 2004
The automatic integration of information resources in the life sciences is one of the most challenging goals facing biomedical informatics today. Controlled vocabularies have played an important role in realizing this goal, by making it possible to draw ...
Anand Kumar, Bada, Barry Smith, Gene Ontology Consortium, Grenon, Hahn, Kumar, Ogren, Schulz, Smith, Smith, Smith   +11 more
core   +1 more source