Results 91 to 100 of about 504,300 (287)
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
A comprehensive survey on the biomedical signal processing methods for the detection of COVID-19. [PDF]
Ann Med Surg (Lond), 2022 Anand S, Sharma V, Pourush R, Jaiswal S.
europepmc +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Current Directions in Biomedical Engineering, 2019 This work presents a new system concept for the prevention, diagnosis and interactive treatment of neck pain. It comprises two measurement units worn at the head and the torso, a smartphone/tablet and a medical assistance software.
Tadayon Puian +3 more
doaj +1 more source
Remote Cell Growth Sensing Using Self-Sustained Bio-Oscillations [PDF]
, 2018 A smart sensor system for cell culture real-time supervision is proposed, allowing for a significant reduction in human effort applied to this type of assay. The approach converts the cell culture under test into a suitable “biological” oscillator.
Daza Navarro, María Paula +9 more
core
Ultra-Resolution Spectral Correction Based on Adaptive Linear Neuron for Biomedical Signal Processing. [PDF]
Front Public Health, 2021 Chen B, Zheng B, Sun W.
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Efficient design of FIR filter based low-pass differentiators for biomedical signal processing
Current Directions in Biomedical Engineering, 2016 This paper describes an alternative design of linear phase low-pass differentiators with a finite impulse response (type III FIR filter). To reduce the number of necessary filter coefficients, the differentiator’s transfer function is approximated by a ...
Wulf Michael +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source