Results 101 to 110 of about 1,046,306 (342)

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

Social participation in the health technology incorporation process into Unified Health System

Revista de Saúde Pública
OBJECTIVE To describe the current process of social participation in the incorporation of health technologies in Brazil, within the context of the Unified Health System (SUS). METHODS A descriptive study was conducted based on the analysis of official
Aline Silveira Silva, Maria Sharmila Alina de Sousa, Emília Vitória da Silva, Dayani Galato   +3 more
doaj   +2 more sources

Wearable Biomedical Measurement Systems for Assessment of Mental Stress of Combatants in Real Time

Sensors, 2014
The Spanish Ministry of Defense, through its Future Combatant program, has sought to develop technology aids with the aim of extending combatants’ operational capabilities.
Fernando Seoane, Inmaculada Mohino-Herranz, Javier Ferreira, Lorena Alvarez, Ruben Buendia, David Ayllón, Cosme Llerena, Roberto Gil-Pita   +7 more
doaj   +1 more source

Health technology assessment of biosimilars worldwide: a scoping review

Health Research Policy and Systems, 2020
Background Health technology assessment (HTA) should provide an assessment of a technology’s effects on health and of the related social, economic, organisational and ethical issues. HTA reports on biosimilars can specifically assess their immunogenicity,
Bruna de Oliveira Ascef, Ana Carolina de Freitas Lopes, Patrícia Coelho de Soárez   +2 more
doaj   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Methodology Report [PDF]

, 2011
Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the ...
Buxton, MJ, Grant, J, Hanney, S, Pollitt, A, Wooding, S   +4 more
core  

A feasibility study for the provision of electronic healthcare tools and services in areas of Greece, Cyprus and Italy [PDF]

, 2011
Background: Through this paper, we present the initial steps for the creation of an integrated platform for the provision of a series of eHealth tools and services to both citizens and travelers in isolated areas of thesoutheast Mediterranean, and on ...
Androulidakis, Aggelos, Bracale, Umberto, Konnis, Georgios, Koutsouris, Dimitrios, Kyriacou, Efthyvoulos, Mougiakakou, Stavroula G., Papadopoulos, Homer, Pattichis, Constantinos S., Pecchia, Leandro, Perakis, Kostas, Tranfaglia, Riccardo   +10 more
core   +7 more sources

Log file‐based quality assurance method for respiratory gating system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon, Young Kyu Lee, Yunji Seol, Chan‐beom Park, Hong Qi Tan, Kyu Hye Choi, Young‐nam Kang, Byung Ock Choi   +7 more
wiley   +1 more source

Growth Characteristic of Fungus strain MGS-2 in a Defined Medium Containing Organic Acids Derived from Peat Soil

Microbiology Indonesia, 2014
Some organic acids derived from lignin degradation in peat soil have significant role in lowering pH of peat soil and have phytotoxic effect for plant.
DIANA NURANI, KOESNANDAR KOESNANDAR
doaj   +1 more source