Results 141 to 150 of about 233,577 (305)

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

WS06: Post Penicillin Antibiotics: From Acceptance to Resistance? (12-May-1998)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “Post penicillin antibiotics” held by the History of Twentieth Century Medicine Group, 12-May-1998. Participants: Dr Geoffrey Asherson, Professor Graham Ayliffe, Dr Derek Bangham, Dr Basil Bard, Dr Ralph ...

core  

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

WS18: Foot and Mouth Disease: The 1967 outbreak and its aftermath (11-Dec-2001)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “Foot and Mouth Disease: The 1967 outbreak and its aftermath” held by the History of Twentieth Century Medicine Group, 11-Dec-2001.

core  

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

WS02c: Drugs in Psychiatric Practice (11-Mar-1997)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “Drugs in Psychiatric Practice” held by the History of Twentieth Century Medicine Group, 11-Mar-1997. Participants: Dr Derek Bangham, Professor George Beaumont, Sir Christopher Booth, Dr Alan Broadhurst ...

core  

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

WS03: Early Heart Transplant Surgery in the UK (10-Jun-1997)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “The First Heart Transplant in the UK in the UK” held by the History of Twentieth Century Medicine Group, 10-Jun-1997.

core  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy