Results 101 to 110 of about 102,446 (342)

Parameter Estimation and Quantitative Parametric Linkage Analysis with GENEHUNTER-QMOD [PDF]

, 2012
Objective: We present a parametric method for linkage analysis of quantitative phenotypes. The method provides a test for linkage as well as an estimate of different phenotype parameters.
Abecasis GR, Almasy L, Birgin EG, Birgin EG, Chen WM, Dietter J, Dietter J, Dudbridge F, Elston RC, Franke D, Gudbjartsson DF, Haseman JK, Holmans P, Kleensang A, Knapp M, Kong A, Konstantin Strauch, Kruglyak L, Kurz T, Kurz T, Lander ES, Lathrop GM, Mattheisen M, Morris N, Pratt SC, Strauch K, Strauch K, Thomas Künzel, Ziegler A   +28 more
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA - net trial [PDF]

, 2013
Background: Group-based social skills training (SST) has repeatedly been recommended as treatment of choice in high-functioning autism spectrum disorder (HFASD). To date, no sufficiently powered randomised controlled trial has been performed to establish
Bender, Stephan, Cholemkery, Hannah, Elsuni, Leyla, Freitag, Christine M., Kieser, Meinhard, Kroeger, Anne K., Kunz, Cornelia Ursula   +6 more
core   +1 more source

BNYVV-derived dsRNA confers resistance to rhizomania disease of sugar beet as evidenced by a novel transgenic hairy root approach [PDF]

, 2010
Agrobacterium rhizogenes-transformed sugar beet hairy roots, expressing dsRNA from the Beet necrotic yellow vein virus replicase gene, were used as a novel approach to assess the efficacy of three intron-hairpin constructs at conferring resistance to ...
Pavli, R., Panopoulos, N.J., Goldbach, R.W., Skaracis, G.N.   +3 more
core   +2 more sources

Associations of Rheumatoid Arthritis Disease Activity with Frailty Over Five Years of Follow‐up

Arthritis Care &Research, Accepted Article.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis registry enrolled from 2003 to 2022 were included. The exposure was RA disease activity measured by Disease Activity Score in 28‐joints (DAS28)
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Selection of a statistical software in the

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2008
Based on the major revision of the regulation for the licence to practice medicine (ÄAppO) we adapted teaching in medical biometry. The so-called “teaching project Biometry” is intended to give basics of biometry to the students by using computer methods.
Babik, Tillmann, Muche, Rainer
doaj  

Ocular biometry and refractive outcomes using two swept-source optical coherence tomography-based biometers with segmental or equivalent refractive indices

Scientific Reports, 2019
This study compared the axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), mean anterior corneal radius of curvature (Rm), and postoperative refractive outcomes obtained from two different swept-source ...
M. Omoto, H. Torii, Sachiko Masui, M. Ayaki, K. Tsubota, K. Negishi   +5 more
semanticscholar   +1 more source

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

Arthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi   +6 more
wiley   +1 more source

Biometry in plant breeding

Crop Breeding and Applied Biotechnology, 2021
In this manuscript we discuss the purpose and scope of biometry and its interactions, complementation, and even overlap with several other areas of genetics.
Cosme Damião Cruz, Pedro Crescêncio Souza Carneiro, Leonardo Lopes Bhering   +2 more
doaj  

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J.T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source