Results 141 to 150 of about 102,446 (342)

Biometry challenges in the longest eyes we have encountered to date

American Journal of Ophthalmology Case Reports
Purpose: This report aims to present biometry challenges and solutions for a patient with the longest eyes we have encountered to date. Observations: A 41-year-old woman with a history of Crouzon syndrome, extreme axial myopia, and posterior segment ...
Raul Plasencia-Salini, Amanda P. Havens, Kevin M. Miller   +2 more
doaj   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Accuracy of axial length measurements obtained by optical biometry and acoustic biometry in rhegmatogenous retinal detachment: a prospective study

Clinical Ophthalmology, 2018
Pear Pongsachareonnont, Sagol Tangjanyatam Vitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand Purpose: We compared ...
Pongsachareonnont P, Tangjanyatam S
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A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Three-versus two-dimensional sonographic biometry for predicting birth weight and macrosomia in diabetic pregnancies [PDF]

, 2016
American College of Obstetricians and Gynecologists, American College of Obstetricians and Gynecologists Committee on Practice Bulletins, Benacerraf, Bland, Boyd, Catalano, Chauhan, DeLong, Hadlock, Johnstone, Jolly, Ju, Lachenbruch, Langer, Lee, Lee, McFarland, Modanlou, Mondestin, Mongelli, Nasrat, Pagani, Sandmire, Scioscia   +23 more
core   +3 more sources

SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics

Advanced Science, EarlyView.
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao, Gaiqin Liu, Jingyi Xia, Runle Chen, Tong Wang, Xiaoling Yang, Ruiling Fang, Yanhong Luo, Ping Zeng, Hongmei Yu, Yanbo Zhang, Yuehua Cui   +11 more
wiley   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Highly Aligned Bacteria Cellulose Yarn Aggregation for Energy Generation and Strain Sensing

Advanced Science, EarlyView.
Although high‐performance bacterial cellulose fibers have attracted significant interest for wearable electronics, a self‐powered and high‐mechanosensitive design is still scarce for achieving an intelligent integrated system. Here, we demonstrate an innovative bio‐fabrication strategy to develop a core‐sheath yarn that features the ordered network and
Chong Gao, Duo Xu, Hui Sun, Sun Ping, Zongxue Gu, Keshuai Liu, Zhiqiang Zhou, Bin Yu, Jian Fang, Weilin Xu   +9 more
wiley   +1 more source

Accuracy of Axial Length Measurements by Two Swept-Source Optical Coherence Tomography Biometers in Macula-off Rhegmatogenous Retinal Detachment Eyes

Clinical Ophthalmology
Hany Ahmed Helaly,* Osama Ramadan Elnaggar,* Mohsen Abou Shousha, Amr Mohamed Elhady Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt*These authors contributed equally to this workCorrespondence: Hany ...
Helaly HA, Elnaggar OR, Abou Shousha M, Elhady AM   +3 more
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