Results 281 to 290 of about 105,792 (367)

Capability Development in the European Medicines Regulatory Network—A European Learning Needs Analysis and Survey Study

Clinical Pharmacology &Therapeutics, EarlyView.
The European Medicines Regulatory Network plays a critical role in safeguarding public health through the assessment and supervision of human medicines. However, rapid scientific and technological advancements have exposed capability deficits across the network, threatening timely and effective regulatory decision‐making.
Naomi Beard, Marko J. Kallio, Luca Kosec, Ulrika Espefält Westin, on behalf of the IncreaseNET consortium   +4 more
wiley   +1 more source

The effect of low-intensity pulsed ultrasound (LIPUS) for the treatment of upper and lower extremity non-union compared to surgical intervention (PiNGUin): study protocol for a national, prospective, randomized controlled, open-label, multicenter, non-inferiority study. [PDF]

Trials
Steinhausen ES, Stang A, Hüsing A, Huessler EM, Brinkmann M, Schröder B, Schröder V, Hohberg-Piel H, Dudda M.   +8 more
europepmc   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Interaction Between Near Work and Narrowband Light on Choroidal Thickness. [PDF]

Invest Ophthalmol Vis Sci
Manoharan MK, Ostrin LA.
europepmc   +1 more source

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia, Bhavya Gandhi, Faisal Quadri, Mahnoor Shahab, Kassie Rong, Genevieve Ramnarine, Ishleen Sudan, Sophia Zhang, Michelle Yu, Sara Mojdehi, Lawrence Mbuagbaw, Anne M. Holbrook   +11 more
wiley   +1 more source

Cataract surgery with autosomal recessive cornea plana caused by a novel <i>KERA</i> mutation. [PDF]

Am J Ophthalmol Case Rep
Abdalla Elsayed MEA, MacLaren RE.
europepmc   +1 more source

Where Tech Meets the SDGs: A Supply‐Chain Process Map for Sustainability Management

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study investigates how advanced technologies support Sustainable Development Goals (SDGs) within supply chain management (SCM) through a structured analysis of 4448 sustainable practices. By integrating perspectives from sustainability‐oriented innovation (SOI) and contingent dynamic capabilities, the research conceptualizes technology ...
Vincenzo Varriale, Antonello Cammarano, Moacir Godinho‐Filho   +2 more
wiley   +1 more source

Automated biometry for assessing cephalopelvic disproportion in 3D 0.55T fetal MRI at term

Uus AU, Bansal S, Gerek Y, Waheed H, Silva SN, Verdera JA, Kyriakopoulou V, Betti L, Jaufuraully S, Hajnal JV, Siasakos D, David A, Chandiramani M, Hutter J, Story L, Rutherford MA.   +15 more
europepmc   +1 more source

Optimization of the Ocular Surface Prior to Cataract Surgery Using Cryopreserved Amniotic Membrane. [PDF]

Clin Ophthalmol
Wongskhaluang J.
europepmc   +1 more source

Artificial Intelligence in Eating Disorder Treatment: A Qualitative Analysis of Clinical Opportunities, Barriers, and Ethical Considerations From Multi‐Disciplinary Focus Groups

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study explored eating disorder and Artificial Intelligence (AI) professionals' perspectives on how AI might support eating disorder treatment. Successful implementation requires insight into implementation partners' perspectives.
J. Maas, S. Franssen, M. Petkovic, S. Cardona Cano, A. E. Dingemans, A. M. van Oosterzee, M. C. T. Slof‐Op ’t Landt, E. Talavera Martinez, C. M. J. M. Vreeswijk, M. Simeunovic‐Ostojic   +9 more
wiley   +1 more source