Results 1 to 10 of about 137,664 (207)

Oxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics

Nature Communications, 2021
Organohalides are widely used as synthetic precursors and target products, but for various halogenation reactions there is a need for effective catalysts to activate commercially available haleniums.
Weijin Wang, Xinyao Li, Xiaoxue Yang, Lingsheng Ai, Zhiwen Gong, Ning Jiao, Song Song   +6 more
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Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Signal Transduction and Targeted Therapy, 2021
Mitochondrial fusion/fission dynamics plays a fundamental role in neuroprotection; however, there is still a severe lack of therapeutic targets for this biological process.
Ke-Wu Zeng, Jing-Kang Wang, Li-Chao Wang, Qiang Guo, Ting-Ting Liu, Fu-Jiang Wang, Na Feng, Xiao-Wen Zhang, Li-Xi Liao, Mei-Mei Zhao, Dan Liu, Yong Jiang, Pengfei Tu   +12 more
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Correction: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Signal Transduction and Targeted Therapy, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41392-021-00533 ...
Ke-Wu Zeng, Jing-Kang Wang, Li-Chao Wang, Qiang Guo, Ting-Ting Liu, Fu-Jiang Wang, Na Feng, Xiao-Wen Zhang, Li-Xi Liao, Mei-Mei Zhao, Dan Liu, Yong Jiang, Pengfei Tu   +12 more
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Icaritin Provides Neuroprotection in Parkinson’s Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency

Antioxidants, 2021
Neuroinflammation, oxidative stress, and mitochondrial dysfunction are all important pathogenic mechanisms underlying motor dysfunction and dopaminergic neuronal damage observed in patients with Parkinson’s disease (PD).
Hao Wu, Xi Liu, Ze-Yu Gao, Ming Lin, Xin Zhao, Yi Sun, Xiao-Ping Pu   +6 more
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Photosensitizer-free visible-light-promoted glycosylation enabled by 2-glycosyloxy tropone donors

Nature Communications, 2023
Photochemical glycosylation has attracted considerable attention in carbohydrate chemistry. However, to the best of our knowledge, visible-light-promoted glycosylation via photoactive glycosyl donor has not been reported.
Jing Zhang, Zhao-Xiang Luo, Xia Wu, Chen-Fei Gao, Peng-Yu Wang, Jin-Ze Chai, Miao Liu, Xin-Shan Ye, De-Cai Xiong   +8 more
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Hyaluronic acid coatings as a simple and efficient approach to improve MSC homing toward the site of inflammation

Scientific Reports, 2017
A major challenge in regenerative medicine is to improve therapeutic cells’ delivery and targeting using an efficient and simple protocol. Mesenchymal stem cells (MSC) are currently employed for the treatment of inflammatory-based diseases, due to their ...
Bruna Corradetti, Francesca Taraballi, Jonathan O. Martinez, Silvia Minardi, Nupur Basu, Guillermo Bauza, Michael Evangelopoulos, Sebastian Powell, Claudia Corbo, Ennio Tasciotti   +9 more
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Eremophilane-Type Sesquiterpenes from a Marine-Derived Fungus Penicillium Copticola with Antitumor and Neuroprotective Activities

Marine Drugs, 2022
Chemical examination of a marine sponge-associated Penicillium copticola fungus resulted in the isolation of ten undescribed eremophilanes, namely copteremophilanes A–J (1–10), along with two new glycosides, 5-glycopenostatin F (11) and 5-glucopenostatin
Jianping Zhang, Dong Liu, Aili Fan, Jian Huang, Wenhan Lin   +4 more
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Silver-catalyzed remote Csp3-H functionalization of aliphatic alcohols

Nature Communications, 2018
Aliphatic alcohols usually require pre-activation for successful functionalization of their carbon chain. Here, the authors report a silver-catalyzed δ-selective functionalization of aliphatic alcohols via Csp3-H bond cleavage under mild conditions ...
Yuchao Zhu, Kaimeng Huang, Jun Pan, Xu Qiu, Xiao Luo, Qixue Qin, Jialiang Wei, Xiaojin Wen, Lizhi Zhang, Ning Jiao   +9 more
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Probabilistic Dual-Space Fusion for Real-Time Human-Robot Interaction

Biomimetics, 2023
For robots in human environments, learning complex and demanding interaction skills from humans and responding quickly to human motions are highly desirable.
Yihui Li, Jiajun Wu, Xiaohan Chen, Yisheng Guan   +3 more
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Immune tuning scaffold for the local induction of a pro-regenerative environment

Scientific Reports, 2017
In mammals, tissue regeneration is accomplished through a well-regulated, complex cascade of events. The disruption of the cellular and molecular processes involved in tissue healing might lead to scar formation.
Bruna Corradetti, Francesca Taraballi, Claudia Corbo, Fernando Cabrera, Laura Pandolfi, Silvia Minardi, Xin Wang, Jeffrey Van Eps, Guillermo Bauza, Bradley Weiner, Ennio Tasciotti   +10 more
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