Results 61 to 70 of about 18,916 (229)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Synovial joint lubrication – does nature teach more effective engineering lubrication strategies? [PDF]

, 2007
Nature shows numerous examples of systems which show energy efficiency, elegance in their design and optimum use of materials. Biomimetics is an emerging field of research in engineering and successes have been documented in the diverse fields of ...
Liskiewicz, T., Morina, A., Neville, A., Yan, Y.   +3 more
core   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Biomimetic rehabilitation engineering: the importance of somatosensory feedback for brain-machine interfaces. [PDF]

, 2016
Brain-machine interfaces (BMIs) re-establish communication channels between the nervous system and an external device. The use of BMI technology has generated significant developments in rehabilitative medicine, promising new ways to restore lost sensory-
Blabe C H, Bondi A B, Bryan M J, Callier T, Chavarriaga R, David Perruchoud, Di Pino G, Duboc L, Ferrez P, Fetz E E, Flint R D, Hebert J S, Iolanda Pisotta, Kuiken T A, Kwak N S, Lebedev M A, Leuthardt E C, McFarland D J, Micah M Murray, Milekovic T, Rupp R, Sainburg R L, Schalk G, Silvio Ionta, Simeral J D, Stefano Carda, Takmakov P, Tan D W, Vidaurre C, Wang S, Wodlinger B, Yin E   +31 more
core   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Inspection of Biomimicry Approaches as an Alternative to Address Climate-Related Energy Building Challenges: A Framework for Application in Panama

Biomimetics, 2020
In the Panama context, energy consumption in the building sector is mostly related to the conditioning of indoor spaces for cooling and lighting. Different nature strategies can be mimic to strongly impact these two aspects in the building sector, such ...
Miguel Chen Austin, Dagmar Garzola, Nicole Delgado, José Ulises Jiménez, Dafni Mora   +4 more
doaj   +1 more source

Looking Inwards for Sustainability: Nigerian Cities and Building Demolition-waste or wealth? [PDF]

, 2015
Cities could generally be described as sustainable before the replacement of manual labour with machines known as the industrial revolution of the 18th century in Europe.
Abdullahi, A. L., Lee, Angela
core  

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Automated Retrieval of Non-Engineering Domain Solutions to Engineering Problems [PDF]

, 2009
Organised by: Cranfield UniversityBiological inspiration for engineering design has occurred through a variety of techniques such as creation and use of databases, keyword searches of biological information in natural-language format, prior knowledge ...
Goeke, M. S., McAdams, D. A., Stone, R. B., Stroble, J. K., Watkins, S. E.   +4 more
core  

Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self‐Assembly within Highly Crowded Microgel Pastes

Advanced Materials, EarlyView.
A new approach to extracellular matrix‐mimetic, hierarchical biomaterials is presented. Soft gels composed of overpacked hydrogel microparticle arrays present a biomolecularly crowded environment permissive to the self‐assembly of collagen networks.
Elif Narbay, Abbygail Caine, Sanika Pandit, Gabrielle Montgomery, Marion Harper, E. Daniel Cárdenas‐Vásquez, Hatte Hamilton, Megan Hicks, Daniel Mattar, Kyle Choy, Marco Bisoffi, L. Andrew Lyon   +11 more
wiley   +1 more source