Results 31 to 40 of about 3,231 (180)

Probing Cinnamamides and Benzamides as Anthelmintics: Discovery of Potent Drug‐Like Agents Against Angiostrongylus cantonensis

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Cynnamoyl benzylpiperazine was identified as drug‐like derivative of cinnarizine with anthelmintic activity against A. cantonensis. In this work, 15 out of 31 derivatives showed improved anthelmintic activity with increased solubility. A SAR study was carried out to determine the molecular features involved in such effect.
Bruna L. Lemes, Mariana A. Siegl‐Breno, Marina T. Varela, Flavia B. Lopes, Mikaelly K. Silva‐Nunes, Thaiane D. Santos, Lucas Fukui‐Silva, Daniel B. Roquini, Vinicius G. Maltarollo, Josué de Moraes, João Paulo S. Fernandes   +10 more
wiley   +1 more source

Observations on two biological races of Schistosoma mansoni

Memorias do Instituto Oswaldo Cruz, 1981
A comparative study of the BH strain of Schistosoma mansoni from Belo Horizonte, Minas Gerais state, infective to Biomphalaria glabrata from the same locality, and the SJ strain from São José dos Campos, São Paulo state, infective to B.
W. Lobato Paraense, Lygia R. Corrêa
doaj   +1 more source

IL‐25 Enhances Eosinophil‐Associated Inflammation in Angiostrongylus cantonensis‐Infected Mice

Parasite Immunology, Volume 48, Issue 6, June 2026.
ABSTRACT This study aimed to investigate the role of interleukin (IL)‐25 in the pathogenesis of angiostrongylosis. We used ICR mice as non‐permissive hosts, divided them into groups and experimentally infected them with infective larvae of the Angiostrongylus cantonensis.
Chih‐Cheng Chuang, Wen‐Bin Wu, Jiun‐Jr Wang, Ming‐Chieh Ma, Wen‐Yuan Du   +4 more
wiley   +1 more source

Long-term controlled field experiment on the competition between two species of Biomphalaria (Mollusca, Basommatophora), the snail vectors of Schistosoma mansoni in Northeastern Brazil Estudo experimental de campo sobre a competição entre duas espécies de Biomphalaria (Mollusca, Basommatophora), vetores do Schistosoma mansoni no Nordeste do Brasil

Cadernos de Saúde Pública, 1993
A long-term controlled field experiment on the interactions of the populations of Biomphalaria glabrata (target population) and B. straminea (competitor) was carried out in the county of Alhandra, state of Paraíba, Brazil, during the period 1980 through ...
Constança S. Barbosa, Frederico S. Barbosa, Francisco Arruda   +2 more
doaj   +1 more source

Conkazal‐M1 from the MKAVA family of conotoxins: A dual‐function protease inhibitor and neuroactive peptide

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney, Thomas Lund Koch, Nicklas Lund Ryding, Aymeric Rogalski, Kevin Chase, Matías Leonel Giglio, Samuel S. Espino, Zildjian G. Acyatan, Maren Watkins, Baldomero M. Olivera, Helena Safavi‐Hemami, Kaare Teilum, Lars Ellgaard   +12 more
wiley   +1 more source

Alguns aspectos da biologia de Biomphalaria glabrata (Say, 1818) e Biomphalaria tenagophila (D'Orbigny, 1835) (Pulmonata, planorbidae): II - Fecundidade e fertilidade Some biological aspects of Biomphalaria glabrata (Say, 1818) and Biomphalaria tenagophila (D'Orbigny, 1835) (Pulmonata, planorbidae): II - Fecundity and fertility

Revista de Saúde Pública, 1977
Foi realizada, comparativamente, a avaliação do número de cápsulas ovíferas e ovos por caramujo e do número de ovos por desova (fecundidade) e a verificação da taxa de eclosão e de ovos férteis (fertilidade) de Biomphalaria glabrata e Biomphalaria ...
Urara Kawazoe
doaj   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, Volume 101, Issue 2, Page 970-1002, April 2026.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

A Benzoic Acid Derivative and Flavokawains from Piper species as Schistosomiasis Vector Controls

Molecules, 2014
The search of alternative compounds to control tropical diseases such as schistosomiasis has pointed to secondary metabolites derived from natural sources.
Ludmila N. Rapado, Giovana C. Freitas, Adriano Polpo, Maritza Rojas-Cardozo, Javier V. Rincón, Marcus T. Scotti, Massuo J. Kato, Eliana Nakano, Lydia F. Yamaguchi   +8 more
doaj   +1 more source

Phytochemical Diversity, Nutritional Values, and Biological Properties of Halopithys incurva (Hudson) Batters, 1902

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Youssra Aalilou, Abdelhakim Bouyahya, Kaoutar Benrahou, Mustapha Hassoun, Hanaa Moussa, Issam Ameziane El Hassani, Waleed Al Abdulmonem, Learn‐Han Lee, Gokhan Zengin, My El Abbes Faouzi   +9 more
wiley   +1 more source

The Pampulha reservoir remains a potential urban focus of schistosomiasis mansoni in Brazil: changes in the occurrence patterns of Biomphalaria species and a new record of the parasite

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction The Pampulha reservoir has long been a focus of schistosomiasis transmission in Belo Horizonte, State of Minas Gerais, Brazil. The last malacological study conducted in this urban reservoir was more than two decades ago, and thus, an update ...
Hudson Alves Pinto, Vitor Luis Tenorio Mati, Alan Lane de Melo   +2 more
doaj   +1 more source