Results 81 to 90 of about 18,629 (199)

The significance of the amoebocyte-producing organ in Biomphalaria glabrata [PDF]

Memórias do Instituto Oswaldo Cruz, 2012
In molluscs, internal defence against microorganisms is performed by a single cell type, i.e., the haemocyte or amoebocyte. The origin of these cells in Biomphalaria glabrata was initially thought to be localised within the vasculo-connective tissue.
Souza, Samaly dos Santos, Andrade, Zilton Araújo   +1 more
openaire   +4 more sources

Pharmacological Inhibition of c‐Jun N‐Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Frederik Stettler, Lukas Knedla, Maximilian Hagen, Verena von Bülow, Heike Müller, Annette Tschuschner, Daniel Zahner, Simone Haeberlein, Max F. Moescheid, Anita Windhorst, Monika Burg‐Roderfeld, Dieter Glebe, Bernardo Pereira Moreira, Céline Lesieur, Andreas Schmid, Franco H. Falcone, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld   +18 more
wiley   +1 more source

CRISPR/Cas9 Knockout of Shell Matrix Protein 1 in the Slipper‐Snail Crepidula atrasolea

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 5, Page 266-283, July 2025.
Methods for CRISPR/Cas9 shell matrix protein knockout in the snail, Crepidula atrasolea including optimizing RNP delivery and embryo husbandry, to the use of Sanger and MiSeq sequencing, and high‐content screening of embryos to characterize the loss of Shell Matrix Protein 1 (SMP1) during larval shell development.
Grant Batzel, Yiqun Wang, Antonia Bock, Elbereth Chen, Stephanie Neal, Rebecca N. Lopez‐Anido, Yoon Lee, Evan Tjeerdema, Emily Ignatoff, Tejasvi Patil, Gabriela Ramirez, Maryna P. Lesoway, Amro Hamdoun, Deirdre C. Lyons   +13 more
wiley   +1 more source

Seleção de linhagens de Biomphalaria tenagophila e Biompnalaria glabrata visando maior suscetibilidade ao Schistosoma mansoni Selection of strains of Biomphalaria tenagophila and Biomphalaria glabrata to improve susceptibility to Schistosoma mansoni

Revista de Saúde Pública, 1978
Utilizando um esquema de seleção individual em progenies autofecundadas, foram obtidas, após quatro gerações, populações de Biomphalaria tenagophila e de Biomphalaria glabrata, altamente suscetíveis às linhagens do Schistosoma mansoni do Vale do Rio ...
José Valfrido de Santana, Luiz Augusto Magalhães, Humberto de Araújo Rangel   +2 more
doaj   +1 more source

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

Unexpected Shifts in Bivalve Function From Filtration to Transmission Risk

Freshwater Biology, Volume 70, Issue 6, June 2025.
ABSTRACT Understanding the complex interactions between filter‐feeding species and zoonotic disease transmission in aquatic environments is crucial for accurately quantifying the ecosystem services provided by these organisms. This study explores for the first time the roles of freshwater bivalves in the transmission dynamics of emerging zoonotic ...
Jakub Hradečný, Divakaran Pandian, Lucia Anettová, Anna Šipková, Juan Felipe Escobar‐Calderón, Mehrak Mohammadi, Kateřina Gregarová, David Modrý, Karel Douda   +8 more
wiley   +1 more source

The Innate Immune Sensor Zbp1 Mediates Central Nervous System Inflammation Induced by Angiostrongylus Cantonensis by Promoting Macrophage Inflammatory Phenotypes

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This study reveals that Zbp1 plays a pivotal role in regulating neuroimmune interactions during Angiostrongylus cantonensis (AC) infection. Zbp1 modulates lymphocyte infiltration and natural killer (NK) cell cytotoxicity by promoting cytokine secretion and M1 polarization of macrophages, shaping the CNS immune microenvironment.
Hongli Zhou, Minyu Zhou, XiPing Liao, Liangyu Zhang, Hang Wei, Yuting Lu, Yiqing Zhang, Hui Huang, Yue Hu, Tao Chen, Zhiyue Lv   +10 more
wiley   +1 more source

Distribuição de Biomphalaria glabrata (Say, 1818) (Pulmonata, Planorbidae) no Estado de São Paulo, Brasil Notes on the distribution of Biomphalaria glabrata (Say, 1818) (Pulmonata, Planorbidae) in the S. Paulo State, Brazil

Revista de Saúde Pública, 1987
São apresentadas informações atualizadas sobre a distribuição geográfcia de Biomphalaria glabrata (Say, 1818) no Estado de São Paulo (Brasil), em razão do importante papel que tal espécie de planorbídeo desempenha na epidemiologia da esquistossomose ...
Horacio Manuel Santana Teles, Jorge Faria Vaz   +1 more
doaj   +1 more source

Comportamento dos amebócitos circulantes de moluscos planorbídeos frente ao parasitismo por larvas de Schistosoma mansoni, inoculação de tinta nanquim e fratura da concha

Revista de Saúde Pública, 1996
Foi estudado o comportamento dos amebócitos circulantes de Biomphalaria glabrata e Biomphalaria tenagophila mediante à infecção pelo Schistosoma mansoni, à inoculação de tinta Nanquim e à fratura da concha.
Seta Luciane de, Magalhães Luiz Augusto, Carvalho José Ferreira de   +2 more
doaj   +3 more sources

Dynamics of snail populations of Biomphalaria glabrata and B. straminea under semi-natural conditions Dinâmica das populações dos caramujos Biomphalaria glabrata e B. straminea em condições semi-naturais

Cadernos de Saúde Pública, 1992
Growth curves and mortality rates for populations of Biomphalaria glabrata and B. straminea bred under semi-natural conditions are reponed. Snail populations of the above species were maintained for 220 weeks in indoor cement channels. Data were recorded
Frederico S. Barbosa, Odécio Sanches, Constança S. Barbosa, Francisco Arruda   +3 more
doaj   +1 more source