Results 111 to 120 of about 101,810 (380)
Advanced Science, EarlyView.Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong +22 more
wiley +1 more source
A Model for Indigenous Development of Biopharmaceutical Industry: The Case of CinnaGen Company [PDF]
بهبود مدیریت, 2019 Recent studies on technological catch-up show a strategic shift from the whole process towards focusing on the processes. Traditionally, scholars were interested in examining the relationship between local and international sources of knowledge through ...
Fatemeh Mojiri +3 more
doaj
Ce‐Doped Lignin‐Based Nanozyme with Heat‐Activated Hydrolase Activity
Advanced Science, EarlyView.A novel Ce‐doped lignin‐based hydrolase nanozyme (Ce‐AL) is synthesized using Ce ions coordinated with aminated industrial lignin. The Ce‐AL effectively hydrolyzes phosphate ester bonds and protein amide bonds, maintain high activity at 100°C, and successfully fights bacteria biofilms.
Xin Liu +7 more
wiley +1 more source
Risk-Return Analysis of the Biopharmaceutical Industry as Compared to Other Industries
Frontiers in Pharmacology, 2018 Background: Profits in the biopharmaceutical industry have been scrutinized in social debate. However, drawing conclusions based on industry profitability only is inappropriate as such an analysis does not account for risks faced by investors. This study
Cedric Popa +4 more
doaj +1 more source
The Future of Generic Biologics: Should the United States “Follow-On” the European Pathway? [PDF]
, 2008 The United States is embarking on a biotechnology drug revolution. In the last few decades, biotech drugs have saved millions of lives, and the market for these miracle cures continues to grow at an astronomical rate.
Kaldre, Ingrid
core +1 more source
(Re)defining biopharmaceutical [PDF]
Nature Biotechnology, 2008 Vested interests are redefining, rebranding and co-opting what is 'biopharmaceutical'. This is not just a matter of semantics-the core identity of the biotech industry and its products is at stake.
openaire +2 more sources
Traceless Regulation of Genetic Circuitry
Advanced Science, EarlyView.Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley +1 more source
ChemEngineeringFed-batch and perfusion bioreactors are commonly used in biopharmaceutical production. This study applies mathematical models to investigate the influence of substrate concentration in the media added (Sm), operating substrate concentration in the ...
John J. Fitzpatrick +5 more
doaj +1 more source
Iowa Developments, April 2003, Vol.12, no.2 [PDF]
, 2003 Resource to help educate businesses or communities about state-sponsored ...
core
Biotechnology Journal, 2006 AbstractThe biopharmaceutical industry, whose products are produced mainly by recombinant DNA technology, antibody technologies and cytotechnology, is the most important sector in industrial biotechnology, and is one of the most rapidly growing high‐tech industries.
Xianwen, Hu, Qingjun, Ma, Shuyong, Zhang
openaire +3 more sources