Results 141 to 150 of about 30,350 (261)

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Author Correction: Acoustic metamaterials-driven transdermal drug delivery for rapid and on-demand management of acute disease. [PDF]

Nat Commun
Xu J, Cai H, Wu Z, Li X, Tian C, Ao Z, Niu VC, Xiao X, Jiang L, Khodoun M, Rothenberg M, Mackie K, Chen J, Lee LP, Guo F.   +14 more
europepmc   +1 more source

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil, Norma A Valdez‐Cruz, Sara Restrepo‐Pineda, Nuria Sánchez‐Puig, Rafael Vázquez‐Duhalt, Rubén D Cadena‐Nava, Néstor O Pérez, Mauricio A Trujillo‐Roldán   +7 more
wiley   +1 more source

Production of Biopharmaceutical Proteins from Scallop Hemocytes as a Bioreactor Using Improved Transfection Conditions. [PDF]

Mar Biotechnol (NY)
Tsuda T, Sakaguchi A, Nagasawa K.
europepmc   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Correction: Dai et al. Mallotucin D, a Clerodane Diterpenoid from <i>Croton crassifolius</i>, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis. <i>Int. J. Mol. Sci.</i> 2022, <i>23</i>, 14217. [PDF]

Int J Mol Sci
Dai X, Sun F, Deng K, Lin G, Yin W, Chen H, Yang D, Liu K, Zhang Y, Huang L.   +9 more
europepmc   +1 more source

Effect of MPATH‐Dx 2.0 on Diagnostic Agreement in the Histopathologic Assessment of Melanocytic Skin Lesions

JEADV Clinical Practice, EarlyView.
To estimate between pathologist agreement using MPATH‐Dx V1.0 and MPATH‐Dx V2.0 a cross‐sectional reading study on four dermatopathologists assessing paired clinical and histopathology images of melanocytic lesions in blinded and unblinded settings was performed.
Belinda Lai, Lin Zhu, Peter M. Ferguson, Blake O'Brien, Tristan Dodds, Gerardo Ferrara, H. Peter Soyer, Richard A. Scolyer, Katy J. L. Bell   +8 more
wiley   +1 more source

Impact of National Drug Price Negotiation policy on the innovation performance of biopharmaceutical industry in China. [PDF]

Front Public Health
Zhu Y, Zhu J, Gao X, Sun Y, Yan H, Du W, Wang Y, Li X.   +7 more
europepmc   +1 more source

Chemical Kinetics of 2‐, 4‐, and 2,4‐Seleno‐Uracils at Low Temperatures: Tautomerizations and Rotamerizations on Inert Matrices

International Journal of Chemical Kinetics, EarlyView.
ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

Artificial intelligence and machine learning-assisted digital applications for biopharmaceutical manufacturing. [PDF]

Biotechnol Prog
Panjwani S, Wei H, Mason J.
europepmc   +1 more source