Results 231 to 240 of about 98,962 (385)

Models attempting to quantify the relationship between drug development and financial return are missing a key element: the effect on post-approval research. [PDF]

Health Aff Sch
Crippen D, Axelsen K.
europepmc   +1 more source

A review of therapeutic protein expression by mammalian cells [PDF]

, 2008
Coco-Martin, J.M., Harmsen, M.M.
core   +1 more source

Activities of the Biopharmaceutical Sciences

, 1998
Yoshiyuki Hashimoto
openalex   +2 more sources

A Collagen IV Matrix Is Required for Guinea Pig Gastric Epithelial Cell Monolayers to Provide an Optimal Model of the Stomach Surface for Biopharmaceutical Screening [PDF]

, 2005
Klairi M. Kavvada, James G. Murray, Vanessa Moore, A.G.A. Coombes, Peter J. Hanson   +4 more
openalex   +1 more source

Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε‐Aminocaproic Acid and Triethylenetetramine

ELECTROPHORESIS, EarlyView.
ABSTRACT The ICH guideline Q14 on analytical procedure development underlines the importance of science and risk‐based methods for the evaluation of the quality of medicines. Ultimately, a pharmaceutical company, the sponsor, is responsible that the analytical method is fit‐for‐purpose during routine use throughout its lifecycle. Part of the analytical
Joanne Baxter, Lori Fitton, Cari E. Sänger ‐ van de Griend   +2 more
wiley   +1 more source

Transformative roles of digital twins from drug discovery to continuous manufacturing: pharmaceutical and biopharmaceutical perspectives. [PDF]

Int J Pharm X
Maharjan R, Kim NA, Kim KH, Jeong SH.
europepmc   +1 more source

Modelling biopharmaceutical manufacture: Design and implementation of SimBiopharma [PDF]

, 2006
Suzanne S. Farid, John Washbrook, Nigel J. Titchener‐Hooker   +2 more
openalex   +1 more source

Epileptic drop attacks: More than just atonic seizures

Epilepsia Open, EarlyView.
Abstract “Drop attacks” are not officially defined by the International League Against Epilepsy. Seizures are characterized by a sudden loss of control over the trunk and posture, leading to falls and injuries, and resolving within a few seconds. Accurately diagnosing the type of seizure is usually difficult due to limitations in clinical documentation
Tomonori Ono, Kazuaki Sato, Ryoko Honda, Hiroshi Otsubo   +3 more
wiley   +1 more source

National Granted Programs and Public Funds for Biopharmaceutical Startups in Japan. [PDF]

Pharmacol Res Perspect
Okuyama R.
europepmc   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source