Results 251 to 260 of about 98,962 (385)

Cross‐continental transmission and host adaptation of Mycobacterium tuberculosis in China unveiled by population history reconstruction and adaptive evolution signal detection

open access: yesiMetaOmics, EarlyView.
This study showed that four Mycobacterium tuberculosis complex (MTBC) sub‐lineages might be introduced into China 1000–400 years ago via Europe‐China dispersal routes, where they diversified into local clades, and later underwent population expansions that coincided with periods of climatic cooling and warfare.
Wei Wu   +16 more
wiley   +1 more source

Optical method supported by machine learning for dynamics of C‐reactive protein concentrations changes detection in biological matrix samples

open access: yesJournal of Biophotonics, EarlyView.
The proposed method is based on an optical system supported by machine learning, that allows to monitoring dynamic of C‐reactive protein (CRP) level changes in near‐real time. Monitoring the presence level of CRP in wastewater might be used to track the spread of diseases or identify areas with increased morbidity.
Patryk Sokołowski   +6 more
wiley   +1 more source

Safety, tolerability and immunogenicity of a quadrivalent recombinant norovirus vaccine (Pichia pastoris) in participants six weeks of age or older: Phase I/IIa trial. [PDF]

open access: yesEmerg Microbes Infect
Chen G   +14 more
europepmc   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

Introduction of Biopharmaceuticals in Europe: A Cross-Sectional Study of Early Diffusion Patterns and Data Availability. [PDF]

open access: yesBioDrugs
Veszelei I   +29 more
europepmc   +1 more source

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