Results 131 to 140 of about 1,034,839 (324)

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Optical-biophysical relationships of vegetation spectra without background contamination

, 2000
For a better evaluation of the accuracy of VIs in estimating biophysical parameters, a "true" VI value attributed only to the vegetation signal and free of any contamination is needed. In this article, pure vegetation spectra were extracted from a set of
Ni, W, Huete, AR, Miura, T, Gao, X
core   +1 more source

Calculation of biophysical indicators through the automatic processing of satellite images

Proceedings of the 4th Workshop on Agri-Food Research. WiA
This work has been done through the project “Telerieg – Remote sensing use for irrigation practice recommendation and monitoring in the SUDOE space” financed by Programme (SUDOE), which supports regional development through European Regional Development Fund (ERDF) co-financing of transnational projects.
Erena Arrabal, Manuel, Sánchez, D., Pecci, J., Lendrino, G., Hernández, Z., García, S.   +5 more
openaire   +2 more sources

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Landscape variation in tree species richness in northern Iran forests.

PLoS ONE, 2015
Mapping landscape variation in tree species richness (SR) is essential to the long term management and conservation of forest ecosystems. The current study examines the prospect of mapping field assessments of SR in a high-elevation, deciduous forest in ...
Charles P-A Bourque, Mahmoud Bayat
doaj   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Fetal aorta assessment and cardiovascular biophysical indices in small for gestational age fetuses

Placenta
Cardiovascular disease ranks among the foremost causes of morbidity in adults and recent studies indicate that the process of atheromatosis appears to commence as early as fetal life. This study examined differences in several fetal aorta parameters between AGA and SGA fetuses.This was a prospective cohort study that included a total of 198 women with ...
Simou, Maria, Sapantzoglou, Ioakeim, Psarris, Alexandros, Daskalaki, Maria-Anastasia, Daskalakis, Georgios   +4 more
openaire   +2 more sources

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Local Illumination Influence on Vegetation Indices and Plant Area Index (PAI) Relationships

Remote Sensing, 2014
Relationships between biophysical parameters and radiometric data have been tested and evaluated by several professionals using empirical and/or physical approaches.
Flávio Jorge Ponzoni, Clayton Borges da Silva, Sandra Benfica dos Santos, Otávio Cristiano Montanher, Thiago Batista dos Santos   +4 more
doaj   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source