Results 201 to 210 of about 1,099,223 (288)

How to Assess Knowledge Cumulation in Environmental Governance Research? Conceptual and Empirical Explorations

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT Environmental governance research (EGR) has been criticized for not being cumulative, despite the importance of cumulative knowledge for evidence‐informed decision‐making in addressing global sustainability problems. However, defining, measuring, and assessing knowledge cumulation in EGR remain challenging.
Jens Newig, Michael Rose
wiley   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi   +9 more
wiley   +1 more source

Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells

open access: yesExploration, EarlyView.
Hypoxia and acidic microenvironments are characteristic features of solid tumors, driving tumor growth, drug resistance, and metastasis. To address these issues, we combined hyperbaric oxygen therapy with rational designed hydroxyethyl starch‐doxorubicin‐copper nanoparticles to modulate the acidic microenvironment of tumors while enhancing the efficacy
Qingyuan Deng   +9 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

A stepwise process for actionable environmental science research

open access: yesFrontiers in Ecology and the Environment, EarlyView.
Scholars have long recognized the social dimensions of environmental problems. Environmental scientists have responded by increasingly focusing on the interactions between nature and social dynamics. This helps reveal problematic interactions that cause environmental challenges, many of which impact human well‐being.
Margaret A Palmer, James W Boyd
wiley   +1 more source

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