Results 241 to 250 of about 260,009 (313)

Stacking Interventions Enhances Carbon Removals and Profitability of Livestock Production Systems

open access: yesAdvanced Science, EarlyView.
The study indicates that stacking multiple interventions aimed at maximising soil organic carbon (SOC) sequestration and enteric methane (CH4) reductions realizes greater abatement and profit do any singular intervention, especially when SOC sequestration accounts for a significant proportion of greenhouse gas emissions (GHG) mitigation. Abstract While
My Pham‐Kieu   +3 more
wiley   +1 more source

Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques

open access: yesAdvanced Science, EarlyView.
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu   +8 more
wiley   +1 more source

Electrochemical‐Genetic Programming of Protein‐Based Magnetic Soft Robots for Active Drug Delivery

open access: yesAdvanced Science, EarlyView.
This manuscript presents a protein‐based soft robot for active drug delivery. Stimuli‐responsive protein is rationally designed and processed into the substrate of robots. Superparamagnetic Fe3O4 nanoparticles are patterned on the substrate using an electrochemical method, enabling the robot to respond to external physical fields.
Hang Zhao   +12 more
wiley   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

open access: yesAdvanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu   +20 more
wiley   +1 more source

Extraterrestrial biophysics

open access: yesInterdisciplinary Science Reviews, 2000
openaire   +2 more sources

Home - About - Disclaimer - Privacy