Results 251 to 260 of about 260,009 (313)

Phytophthora Disrupts Plant Immunity by Manipulating Nitric Oxide Homeostasis Through GSNOR Inhibition

Advanced Science, EarlyView.
Phytophthora capsici effector PcRD18 targets tomato GSNOR to disrupt NO homeostasis, promoting S‐nitrosylation of immune proteins like RBOHD. This suppresses ROS bursts and promotes pathogen infection. Mutation of the PcRD18‐binding sites of GSNOR avoids pathogen manipulation and offers a strategy to enhance crop resistance. Abstract Nitric oxide (NO),
Tingting Li, Jing Kang, Haizhu Zhang, Lina Wang, Minghui Lu, Lin Cai, Jianming Li, Matthieu H. A. J. Joosten, Yu Du   +8 more
wiley   +1 more source

Structural pathway for PI3-kinase regulation by VPS15 in autophagy. [PDF]

Science
Cook ASI, Chen M, Nguyen TN, Cabezudo AC, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH.   +12 more
europepmc   +1 more source

Strong and Fatigue‐Resistant Hydrogels via Poor Solvent Evaporation Assisted Hot‐Stretching for Tendon Repair

Advanced Science, EarlyView.
An anisotropic hydrogel (AHs) is prepared in this study. The strength of AHs can reach up to 33.14 ± 2.05 MPa, and it exhibits unique defect‐insensitive characteristics. Cracks can only deflect along the fiber alignment direction, demonstrating an interesting self‐protection function.
Huamin Li, Ying Zhang, Haidi Wu, Zhanqi Liu, Cheng Guan, Jin Zhang, Jingyi Chen, Shaohua He, Xuewu Huang, Wancheng Gu, Yiu Wing Mai, Jiefeng Gao   +11 more
wiley   +1 more source

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin, Zhifang Li, Senwei Tan, Qinghui Xiao, Qingcan Li, Jiao Ye, Yifan Zhou, Yan Wan, Qiang Liu, Bijoy K Menon, Bo Hu   +10 more
wiley   +1 more source

Correction to Supporting Information for Takaki and Thirumalai, Sequence complexity and monomer rigidity control the morphologies and aging dynamics of protein aggregates. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Advanced 3D Cell Culture Technologies and Formats. [PDF]

Bioengineering (Basel)
Kasper C, Egger D.
europepmc   +1 more source

Effectiveness of Non-Invasive Methods in Studying Jaguar (<i>Panthera onca)</i> Hair. [PDF]

Animals (Basel)
Rodrigues LP, Raad P, Santos DCD, Almeida AA, Costa VE, Mota LSLSD.   +5 more
europepmc   +1 more source

STCDB4ND: a signal transduction classification database for neurological diseases. [PDF]

Database (Oxford)
Gong B, Li S, Chen Y, Liu L, Hofestädt R, Chen M.   +5 more
europepmc   +1 more source

Topology-based metrics for finding the optimal sparsity in gene regulatory network inference. [PDF]

Bioinformatics
Lundqvist N, Garbulowski M, Hillerton T, Sonnhammer ELL.   +3 more
europepmc   +1 more source

Revisiting lipid nanoparticle composition and structure: A critical take on simulation approaches. [PDF]

Proc Natl Acad Sci U S A
Trollmann MFW, Rossetti P, Böckmann RA.
europepmc   +1 more source