Results 151 to 160 of about 28,795 (286)

Low‐Field MRI as a Multiparametric Tool for Large Engineered Tissue Characterization

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Advances in 3D bioprinting have enabled the fabrication of large and complex engineered tissues, but their increasing size demands non‐invasive tools for monitoring structure, maturation, and perfusion. Magnetic Resonance Imaging (MRI) offers unique multiparametric capabilities, yet high‐field systems remain costly and inaccessible for most ...
Yilbert Gimenez, Valernst Martial Gilmus, Elliott Cowles, Lucie Essayan, Vincent Semet, Michel Cabrera, Christophe A. Marquette, Simon A. Lambert, Emma Petiot   +8 more
wiley   +1 more source

A Multi-Crosslinkable Methacrylated Alginate-GelMa Bioink for Drop-on-Demand Bioprinting. [PDF]

Macromol Biosci
A multi‐crosslinkable methacrylated oxidized alginate–GelMA system enables precise drop‐on‐demand bioprinting by integrating tailored polymer functionality with tunable hydrogel properties. The designed macromolecular network combines photochemical, dynamic covalent, and ionic interactions to achieve printable, cytocompatible bioinks for advanced three‐
Bui T, Karakaya E, Faber J, Röder J, Teßmar J, Bauer J, Friedrich O, Budday S, Boccaccini AR, Detsch R.   +9 more
europepmc   +2 more sources

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian, Pedram Asadi Sarabi, Abbas Piryaei, Massoud Vosough   +3 more
wiley   +1 more source

Advancements in sustainable bioprinting: Materials, challenges and opportunities in transition from 3D to 4D printing

Biomedical Engineering Advances
Bioprinting has emerged as a transformative technology in regenerative medicine, tissue engineering, and biomedical research by enabling the precise fabrication of biologically functional constructs.
Rotan Kumar Saha, Mahedi Hassan, Md. Ripon Ali, Md. Mominul Islam, Apurbo Das   +4 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Substrate stiffness regulates cell fate and its applications in the repair of motor system: From two dimensions to three dimensions

BMEMat, EarlyView.
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu, Renwang Sheng, Ludvig J. Backman, Chuanquan Liu, Danning Zheng, Wei Zhang, Jialin Chen   +6 more
wiley   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Engineering an artificial trachea: Quantitative benchmarks and modular strategies for mechanics, epithelialization, and vascular integration

FlexMat, EarlyView.
In this work, we first examine the limitations of surgical repair and stenting, including migration, granulation, mucus plugging, and infection. We then translate these failures into engineering constraints involving geometry, mechanics, fixation, degradation, junctional stress, and remodeling.
Yiwei Xu, Hanqing Dai, Qianwang Ye, Wanlu Zhang, Na Wang, Lei Xiong, Ruiqian Guo   +6 more
wiley   +1 more source

"3D Bioprinting: Bioinks used and printing techniques for regenerative medicine"

openQuesto studio esplora l'impiego del bioprinting 3D nella medicina rigenerativa, concentrandosi sull'analisi e la caratterizzazione dei bioink e sulle tecniche di stampa utilizzate.
BRUNETTA, GIOVANNI
core  

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

iNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source