Results 181 to 190 of about 41,669 (332)

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

Equine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska, Bernard Turek, Tomasz Jasiński, Michał Kaczorowski, Natalia Kozłowska, Julia Higuchi, Małgorzata Domino   +6 more
wiley   +1 more source

Bioactive Magnesium Silicate Activating Myocardial Energy Metabolism For Infarcted Myocardium Repair

Exploration, EarlyView.
ABSTRACT The heart is a highly energy‐dependent organ, developing bioenergy‐activating biomaterials to activate myocardial adenosine triphosphate (ATP) production and restore dysregulated energy homeostasis is a promising solution for its functional recovery.
Zhibin Liao, Chen Qin, Erhong Song, Chengbin Ding, Zhixu Wang, Yan Sun, Chen Song, Junjie Liu, Jingge Ma, Hongjian Zhang, Leyu Wang, Chengtie Wu   +11 more
wiley   +1 more source

Human coronary artery organ‐chip with circulating immune cells recapitulates anti‐inflammatory effect of pulsatile wall strain

Interdisciplinary Medicine, EarlyView.
A fully characterised organ‐on‐a‐chip model of the human coronary artery with endothelial and smooth muscle cells, plus circulating immune cells, created on the Emulate platform. The model successfully recapitulates the physiological effects of pulsatile vessel dilation on cell morphology and the localised inflammatory susceptibility to TNF‐α ...
Yu Hou, Georgios Ziakas, Tim Hopkins, Wen Wang, Hazel R. C. Screen, Martin M. Knight   +5 more
wiley   +1 more source

Current Developments in 3D Bioprinting for Tissue and Organ Regeneration–A Review [PDF]

, 2020
Swarnima Agarwal, Shreya Saha, Vamsi Krishna Balla, Aniruddha Pal, Ananya Barui, Subhadip Bodhak   +5 more
openalex   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Multi-physical field control piezoelectric inkjet bioprinting for 3D tissue-like structure manufacturing

Huixuan Zhu, Run Li, Song Li, Kai Guo, Cheng‐Ao Ji, Feiyang Gao, Yuejing Zheng, Runyang Zhu, Heran Wang, Liming Zhang, Lianqing Liu, Xiongfei Zheng   +11 more
openalex   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

3D bioprinting of tissues and organs for systemic diseases and localized injuries. [PDF]

Mil Med Res
Ng WL, Bartolo P.
europepmc   +1 more source

Bioprinting Technology as a Legal Challenge: Determining the Model of Legal Regulation

, 2019
Д. Е. Богданов
openalex   +2 more sources

Tissue Bioprinting : A granular approach

The field of bioprinting aims to fabricate tissues and organs that can be used to model drug efficacy and disease mechanisms, repair and ultimate replace dysfunctional parts in living beings. It utilizes computer aided design to create a construct that mimics native tissue, by adding step-by-step every detail of the complex multiscale hierarchical ...
openaire   +1 more source