Results 201 to 210 of about 41,669 (402)

Biomedical applications of silk and its role for intervertebral disc repair

JOR SPINE, Volume 5, Issue 4, December 2022., 2022
For years, researchers have been seeking a suitable biomaterial to repair and/or regenerate the intervertebral disc (IVD) and a promising candidate to fill this gap could be the application of silk. Therefore, this review aims to elaborate on the different origins from which silk is harvested, the characteristics of each silk type and how it can be ...
Andreas S. Croft, Eugenia Spessot, Promita Bhattacharjee, Yuejiao Yang, Antonella Motta, Michael Wöltje, Benjamin Gantenbein   +6 more
wiley   +1 more source

Microfluidics‐Based Microcarriers for Live‐Cell Delivery

Advanced Science, EarlyView.
In this review, recent advancements in microfluidics‐based microcarriers for live‐cell delivery are highlighted. The structural designs of microfluidic‐derived cell‐laden microcarriers are systematically categorized, emphasizing innovative approaches in the fabrication of microspheres, microfibers, and microneedles.
Zhonglin Fang, Xinyuan Yang, Chong Wang, Luoran Shang   +3 more
wiley   +1 more source

Toward 3D‐Bioprinted Models of the Liver to Boost Drug Development

Macromolecular Bioscience, Volume 22, Issue 12, December 2022., 2022
During preclinical studies, bidimensional in vitro models and animal models are synergically exploited to forecast safety and efficacy. 3D‐bioprinting is exploited to produce complex in vitro models, able to mimic physiological and pathological conditions, thus aiming to overcome the conventional paradigm.
Giuseppe Guagliano, Cristina Volpini, Francesco Briatico‐Vangosa, Antonia Icaro Cornaglia, Livia Visai, Paola Petrini   +5 more
wiley   +1 more source

Reinforced Granular Hydrogels Scaffolds with Tunable Physicochemical Properties for Advanced Skin Tissue Engineering

Advanced Science, EarlyView.
This work introduces a highly customizable granular hydrogel scaffold, designed from reactive microparticles through binary macromonomer microdroplet assembly, achieving a precise balance of mechanical strength and biological functionality. Abstract Engineering bioscaffolds with tailored architectures and optimized physicochemical properties remains a ...
Jing Zhang, Yijia Wang, Yue Liu, Guanfu Wu, Guilong Lu, Yue Li, Yu Shen, Caifeng Wang, Mehdi Khanmohammadi, Wojciech Święszkowski, Jing Wang, Ziyi Yu   +11 more
wiley   +1 more source

High-throughput antibody screening with high-quality factor nanophotonics and bioprinting [PDF]

arXiv
Empirical investigation of the quintillion-scale, functionally diverse antibody repertoires that can be generated synthetically or naturally is critical for identifying potential biotherapeutic leads, yet remains burdensome. We present high-throughput nanophotonics- and bioprinter-enabled screening (HT-NaBS), a multiplexed assay for large-scale, sample-
arxiv  

A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks [PDF]

, 2016
Ratima Suntornnond, Edgar Yong Sheng Tan, Jia An, Chee Kai Chua   +3 more
openalex   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

Advanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang, Zhiyuan Zheng, Shilu Zhu, Liang Xu, Qingdong Zhang, Jie Gao, Min Ye, Shuwei Shen, Jinyu Xing, Ming Wu, Ronald X. Xu   +10 more
wiley   +1 more source

Outermost Cationic Surface Charge of Layer‐by‐Layer Films Prevents Endothelial Cells Migration for Cell Compartmentalization in Three‐Dimensional Tissues

Advanced Science, EarlyView.
A nanometer‐sized artificial basement membrane (A‐BM) is developed to replicate the barrier functions of the basement membrane and prevent cell migration. It is demonstrated that the outermost cationic surface charge of nanofilms can effectively inhibit endothelial cell migration and sprouting, allowing for the construction of 3D patterned vascular ...
Jinfeng Zeng, Sven Heilig, Matthias Ryma, Jürgen Groll, Congju Li, Michiya Matsusaki   +5 more
wiley   +1 more source

3-Dimensional Bioprinting of Cardiovascular Tissues

JACC: Basic to Translational Science, 2021
Summary: Three-dimensional (3D) bioprinting may overcome challenges in tissue engineering. Unlike conventional tissue engineering approaches, 3D bioprinting has a proven ability to support vascularization of larger scale constructs and has been used for ...
Kevin Sung, MD, Nisha R. Patel, BS, Nureddin Ashammakhi, MD, PhD, Kim-Lien Nguyen, MD   +3 more
doaj  

Droplet impact on elastic substrates: force scaling crossover [PDF]

arXiv
Droplet impacts are fundamental to fluid-structure interactions, shaping processes from erosion to bioprinting. While previous scaling laws have provided insights into droplet dynamics, force scaling laws remain insufficiently understood, particularly for soft substrates where both the droplet and substrate deform significantly.
arxiv