Results 51 to 60 of about 4,076 (215)

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, Volume 177, Issue 4, Page 810-823, April 2026.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis ‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and
Felipe T. Lima   +9 more
wiley   +1 more source

Identification of New Ocellatin Antimicrobial Peptides by cDNA Precursor Cloning in the Frame of This Family of Intriguing Peptides

open access: yesAntibiotics, 2020
Ocellatins are a family of antimicrobial peptides found exclusively in the Leptodactylus genus. To date, 10 species have been studied and more than 23 peptides described.
Mariela M. Marani   +5 more
doaj   +1 more source

Paranaguá Estuarine Complex Diatoms: Morphology and Molecular Taxonomy

open access: yesBrazilian Archives of Biology and Technology, 2022
The Paranaguá Estuarine Complex (PEC) is one of Brazil's largest southwest Atlantic estuarine systems, possessing a rich microalgae diversity that remains to be fully explored.
Viviane de Fátima Moura Aguillar Rampinelli   +11 more
doaj   +1 more source

Integrated Bioprospection of Phenolics as Potent Modulators of Acinetobacter baumannii Penicillin‐Binding Protein 1A

open access: yesJournal of Chemistry, Volume 2026, Issue 1, 2026.
Diseases caused by carbapenem‐resistant Acinetobacter baumannii can lead to death within 48 h of hospitalization, with an overall mortality rate of 68%. The reduced affinity of carbapenem and other β‐lactams for penicillin‐binding proteins 1A (PBP1A), a critical protein, is a key resistance mechanism in A. baumannii.
Oladunni Ayodele   +2 more
wiley   +1 more source

Bioprospecting

open access: yes, 2001
UCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de ...
Mateo, Nicolás   +2 more
openaire   +2 more sources

Metabolite Screening From Pinus pinea Needles Reveals (+)‐Isocupressic Acid as a Key Phytotoxin for Weed Management

open access: yesPhytochemical Analysis, Volume 36, Issue 8, Page 2374-2384, December 2025.
This study explores the phytotoxicity of Pinus pinea needle extracts and metabolites to evaluate their potential for controlling dicotyledonous weeds. A strategy based on GC–MS, NMR, and optical methods revealed an array of aromatic compounds which are of crucial interest for phytochemical research. Hence, a bio‐guided purification led to the isolation
Hajer Hlaili   +11 more
wiley   +1 more source

Computational Bioprospection of Selected South African Essential Oils for Inhibition of Aldose Reductase and Sorbitol Dehydrogenase for Diabetes Therapy

open access: yesChemistrySelect, Volume 10, Issue 43, November 17, 2025.
This study computationally identifies quercetin‐7‐O‐glucoside (Q7G) as a potential dual inhibitor of aldose reductase and sorbitol dehydrogenase, and quercetin‐3,7‐diglucoside (Q37DG) as a potential sorbitol dehydrogenase inhibitor. These two compounds are traceable to South African Agathosma betulina essential oils and have remarkable binding ...
Oluwaseye Adedirin, Saheed Sabiu
wiley   +1 more source

Bioprospecting plant-associated microbiomes

open access: yesJournal of Biotechnology, 2016
There is growing demand for new bioactive compounds and biologicals for the pharmaceutical, agro- and food industries. Plant-associated microbes present an attractive and promising source to this end, but are nearly unexploited. Therefore, bioprospecting of plant microbiomes is gaining more and more attention.
Müller, Christina Andrea   +2 more
openaire   +4 more sources

Unveiling the Evolutionary History of European Vipers and Their Venoms From a Multi‐Omic Approach

open access: yesMolecular Ecology, Volume 34, Issue 21, November 2025.
ABSTRACT Snake genomes attract significant attention from multiple disciplines, including medicine, drug bioprospection, and evolutionary biology. However, genomic research within the Viperidae family has mostly focused on the subfamily Crotalinae, while the true vipers (Viperinae) have largely been overlooked.
Adrián Talavera   +15 more
wiley   +1 more source

Bioprospecting—fuels from fungi [PDF]

open access: yesBiotechnology Letters, 2015
The world has a continuing demand and utility for liquid fuels to power its societies. The utilization of crude oil based fuels is leading to a dramatic increase in the CO2 content of the atmosphere which is being related to a dangerously warming earth. Having liquid fuels that are derived from biological sources is one solution to this growing problem
openaire   +2 more sources

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