Results 171 to 180 of about 29,628 (262)

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

open access: yesThe Journal of Pathology, Volume 269, Issue 2, Page 164-181, June 2026.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen   +14 more
wiley   +1 more source

Is Saturation Biopsy Still a Viable Alternative to Fusion Biopsy in the Era of Multiparametric MRI? A Comparative Analysis in Patients With Prior Negative Biopsy

open access: yesThe Prostate, Volume 86, Issue 9, Page 990-996, June 15, 2026.
ABSTRACT Background We aimed to compare the diagnostic accuracy of transrectal ultrasound (TRUS)‐guided saturation biopsy (SB) and multiparametric MRI (mpMRI)‐TRUS fusion‐guided combined biopsy (CB) in patients with prior negative prostate biopsies. Methods We retrospectively analyzed data from 160 patients who underwent transrectal prostate biopsy ...
Arda Taşkın Taşkıran   +1 more
wiley   +1 more source

Clinical Utility of Stillbirth Investigations in Australia: A Cohort Study

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Stillbirths impact over two million parents globally every year. Despite current knowledge, technology, and investigations, many stillbirths remain unexplained and are not fully investigated. An important step forward in addressing this gap is determining which investigations produce the highest utility in identifying the cause of ...
Tania Marsden   +22 more
wiley   +1 more source

Multimodal Assessment of Kidney Quality During 24‐h of Normothermic Machine Perfusion

open access: yesArtificial Organs, Volume 50, Issue 6, Page 851-865, June 2026.
Normothermic machine perfusion (NMP) has emerged as a promising tool for assessing kidney quality prior to transplantation; however, reliable biomarkers remain to be established. In this study, thirteen porcine kidneys were perfused for 24 h using an autologous leukocyte‐filtered whole blood‐based perfusate applying urine recirculation.
Marlene Pühringer   +22 more
wiley   +1 more source

Targeted microwave ablation of localised prostate cancer (VIOLETTE trial): a prospective multicentre study

open access: yesBJU International, Volume 137, Issue 6, Page 1032-1039, June 2026.
Objective To assess the oncological outcomes of targeted microwave ablation (TMA) using organ‐based tracking (OBT) Fusion® via KOELIS Trinity® (KOELIS, Meylan, France) in men with intermediate‐risk prostate cancer (PCa): the VIOLETTE trial (ClinicalTrials.gov identifier: NCT04582656) Patients and Method In this prospective phase II, multicentre ...
Nicolas Barry Delongchamps   +11 more
wiley   +1 more source

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