Results 111 to 120 of about 2,118,431 (433)

Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

Molecular Cancer, 2019
Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic treatments, surgical resection and/or biopsy specimens are still generally ...
Qianwei Ye, Sunbin Ling, Shusen Zheng, Xiao Xu   +3 more
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Systematic Review and Meta-Analysis of Native Kidney Biopsy Complications.

American Society of Nephrology. Clinical Journal, 2020
BACKGROUND AND OBJECTIVES Native kidney biopsies are commonly performed in the diagnosis of acute kidney diseases and CKD. Because of the invasive nature of the procedure, bleeding-related complications are not uncommon. The National Institutes of Health,
E. Poggio, R. McClelland, K. Blank, S. Hansen, S. Bansal, A. Bomback, P. Canetta, P. Khairallah, Krzysztof Kiryluk, S. Lecker, G. McMahon, P. Palevsky, S. Parikh, S. Rosas, K. Tuttle, M. Vazquez, A. Vijayan, B. Rovin   +17 more
semanticscholar   +1 more source

Minimally Invasive Optical Biopsy for Oximetry [PDF]

, 2017
The study of localised oxygen saturation in blood vessels can shed light on the etiology and progression of many diseases with which hypoxia is associated.
Brewer, James M., Harvey, Andrew R., van der Putten, Marieke A.   +2 more
core   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Framework for 3D TransRectal Ultrasound [PDF]

Johns Hopkins University "Prostate Day", Baltimore : \'Etats-Unis d'Am\'erique (2008), 2008
Prostate biopsies are mainly performed under 2D TransRectal UltraSound (TRUS) control by sampling the prostate according to a predefined pattern. In case of first biopsies, this pattern follows a random systematic plan. Sometimes, repeat biopsies can be needed to target regions unsampled by previous biopsies or resample critical regions (for example in
arxiv  

Gold-standard of HER2 breast cancer biopsies using supervised learning based on multiple pathologist annotations [PDF]

arXiv, 2022
Breast cancer is one of the most common cancer in women around the world. For diagnosis, pathologists evaluate biomarkers such as HER2 protein using immunohistochemistry over tissue extracted by a biopsy. Through microscopic inspection, this assessment estimates the intensity and integrity of the membrane cells' staining and scores the sample as 0, 1+,
arxiv  

A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer.

New England Journal of Medicine, 2003
BACKGROUND Although numerous studies have shown that the status of the sentinel node is an accurate predictor of the status of the axillary nodes in breast cancer, the efficacy and safety of sentinel-node biopsy require validation.
U. Veronesi, G. Paganelli, G. Viale, A. Luini, S. Zurrida, V. Galimberti, M. Intra, P. Veronesi, C. Robertson, P. Maisonneuve, G. Renne, C. De Cicco, F. De Lucia, R. Gennari   +13 more
semanticscholar   +1 more source

Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer's Precision Medicine and Pharmacology. [PDF]

, 2019
Systems biology studies have demonstrated that different (epi)genetic and pathophysiological alterations may be mapped onto a single tumor's clinical phenotype thereby revealing commonalities shared by cancers with divergent phenotypes.
Goetzl, Edward J, Hampel, Harald, Kapogiannis, Dimitrios, Lista, Simone, Vergallo, Andrea   +4 more
core   +2 more sources

A lab-on-a-disc platform enables serial monitoring of individual CTCs associated with tumor progression during EGFR-targeted therapy for patients with NSCLC [PDF]

, 2020
Rationale: Unlike traditional biopsy, liquid biopsy, which is a largely non-invasive diagnostic and monitoring tool, can be performed more frequently to better track tumors and mutations over time and to validate the efficiency of a cancer treatment ...
Cho, Yoon-Kyoung, Jeong, Hyoung-oh, Kim, Gwang Ha, Kim, Mi-Hyun, Lee, Kyusang, Lee, Semin, Lim, Minji, Lowe, Alarice C., Park, Hee Chul, Park, Juhee   +9 more
core   +1 more source