Results 151 to 160 of about 745,933 (211)

A Microfluidic Multiplex Sorter for Strain Development

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves   +6 more
wiley   +1 more source

Mucosa‐Interfacing Capsule for In Situ Sensing the Elasticity of Biological Tissues

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A fundamental mechanism of palpating soft materials is reported to sense deep tissue elasticity in situ with minimal invasion using the interaction between the robot palpation unit and soft tissues. Both the robot locomotion and elasticity sensing functions are remotely controlled by external magnetic fields, while the sensing data are wirelessly ...
Kiyoung Kim   +10 more
wiley   +1 more source

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

open access: yesAdvanced Materials Technologies, EarlyView.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha   +10 more
wiley   +1 more source

One‐Step Covalent Biofunctionalization of Tubular Constructs Enabled by Surface‐Embedded Radicals

open access: yesAdvanced Materials Technologies, EarlyView.
Uniform covalent biofunctionalization of tubular constructs is achieved in one step using surface‐embedded radicals generated by a novel plasma immersion ion implantation (PIII) technology. This scalable, solvent‐free technology advances bioengineered tubes for tissue engineering and implant applications.
Anyu Zhang   +12 more
wiley   +1 more source

Smart Sampling Capsule for Capture and Detection of Enteric Pathogens in the Small Intestine

open access: yesAdvanced Materials Technologies, EarlyView.
An ingestible smart sampling capsule for capturing asymptomatic enteric pathogens at their primary sites of interaction within the small intestine. This capability enables non‐invasive detection of early pathogen colonization within the gut environment prior to fecal shedding, providing a robust approach for pathogen surveillance and microbiome studies.
Akshay Krishnakumar   +6 more
wiley   +1 more source

A Hydrophilic Hollow Microneedle Platform for Sampling Interstitial Fluid and On‐Site Biomarker Detection

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a superhydrophilic 3D‐printed hollow microneedle patch for continuous interstitial fluid (ISF) extraction and on‐patch biomarker sensing. Combining projection micro‐stereolithography and chemical vapor deposition, high‐resolution microneedles with enhanced wettability are fabricated, enabling passive ISF uptake without external ...
Taher Abbasiasl   +7 more
wiley   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan   +12 more
wiley   +1 more source
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Liquid biopsy enters the clinic — implementation issues and future challenges

Nature Reviews Clinical Oncology, 2021
Michail Ignatiadis   +2 more
exaly   +2 more sources

Application of exosomes as liquid biopsy in clinical diagnosis

open access: yesSignal Transduction and Targeted Therapy, 2020
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small extracellular vesicles with sizes between 30–150 nm.
Biting Zhou, Kailun Xu, Xi Zheng
exaly   +2 more sources

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