Results 1 to 10 of about 7,520 (138)
Chronic sustained hypoxia (CSH), as found in individuals living at a high altitude or in patients suffering respiratory disorders, initiates physiological adaptations such as carotid body stimulation to maintain oxygen levels, but has deleterious effects
Jesus Prieto-Lloret +7 more
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An Evolutionary Perspective of the Lipocalin Protein Family
The protein family of Lipocalins is ubiquitously present throughout the tree of life, with the exception of the phylum Archaea. Phylogenetic relationships of chordate Lipocalins have been proposed in the past based on protein sequence similarities, but ...
Sergio Diez-Hermano +4 more
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Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Microglia are brain-resident myeloid cells and play a major role in the innate immune responses of the CNS and the pathogenesis of Alzheimer's disease (AD).
Clara Muñoz-Castro +14 more
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Physiology and Pathophysiology of Oxygen Sensitivity
Oxygen is an essential requirement for metabolism in mammals and many other animals. Therefore, pathways that sense a reduction in available oxygen are critical for organism survival.
Robert S. Fitzgerald, Asuncion Rocher
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Machine Learning Representation of Loss of Eye Regularity in a Drosophila Neurodegenerative Model
The fruit fly compound eye is a premier experimental system for modeling human neurodegenerative diseases. The disruption of the retinal geometry has been historically assessed using time-consuming and poorly reliable techniques such as histology or ...
Sergio Diez-Hermano +4 more
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La situación extrema surgida a fines del 2019 debido a la pandemia de la Covid-19 impuso la búsqueda de alternativas para continuar el desarrollo del proceso de enseñanza-aprendizaje en la educación superior.
Georgina Espinosa López +5 more
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The plasma membrane of cells from rat submandibular glands was isolated and extensively sonicated. The homogenate was centrifuged at high speed in a discontinuous sucrose gradient.
Mikel Garcia-Marcos +9 more
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Doctora en C.C. Químicas por la Universidad Complutense de Madrid en la especialidad de Bioquímica y Biología Molecular. Su carrera científica se sitúa principalmente en Suecia (Universidad de Lund) y Noruega donde ha trabajado tanto en industria como ...
Aranzazu Berbey Álvarez
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A Model for ERD2 Function in Higher Plants
ER lumenal proteins have a K(H)DEL motif at their C-terminus. This is recognized by the ERD2 receptor (KDEL receptor in animals), which localizes to the Golgi apparatus and serves to capture escaped ER lumenal proteins.
David G. Robinson, Fernando Aniento
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