Results 121 to 130 of about 49,736 (242)
Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice
Andrology, EarlyView.ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang +4 more
wiley +1 more source
Modeling and analyzing the agroecological performance of farms with ECOPATH [PDF]
Intensive and integrated resource management, where field crops, vegetables, trees, livestock and fish production are combined through efficient reuse of wastes, residues, by-products and external inputs, offers a potential avenue towards a productive ...
Dalsgaard, J.P.T., Oficial, R.T.
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Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
Fish powder as a low-cost component in media for producing bacterial cellulose [PDF]
, 2012 Some bacteria can produce extracellular bacterial cellulose (BC). This polysaccharide is chemically identical to cellulose produced by plants but has no associated lignin and hemicelluloses. The unique mechanical properties, chemical stability and purity
Adnan, Azila Binti +3 more
core +1 more source
E3 ligase Praja1 mediates ubiquitination and degradation of microtubule‐associated protein tau
The FEBS Journal, EarlyView.E3 ligase Praja1, but not its paralogue Praja2, recognizes and ubiquitinates tau protein for proteasomal degradation. This newly identified function of Praja1‐mediated tau degradation suggests its role in protein quality control, which may provide insights into the pathogenesis of tauopathies.
Shiho Aoki +8 more
wiley +1 more source
Effect of false flax oilcake in thermophilic biogas production [PDF]
, 2009 False flax oilcake has been found to be suitable for anaerobic fermentation in mixtures with cattle slurry and straw. In organic farms, digestion of cattle dung and wheat straw with 8 % dry matter content mixed with 5 % of total material weight false ...
Böhm, Herwart +4 more
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The FEBS Journal, EarlyView.In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
Environmental Dynamics in Animal Waste Reclamation in the Scaling up of Livestock in Thailand [PDF]
, 2012 Thailand has seen a scaling up of pig production in numbers and structure. Nonetheless, in-house separation and agricultural reclamation of pig solid waste are common practice.
GONZALEZ-SORIA, JAVIER
core
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
The FEBS Journal, EarlyView.Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito +8 more
wiley +1 more source