Results 161 to 170 of about 46,007 (267)

Cucurbit[8]Uril Achieved Single‐Molecule Chiral Transfer to Supramolecular Circularly Polarized Luminescence

open access: yesAdvanced Science, EarlyView.
A single‐molecule cascade supramolecular system comprising L/D‐FPy, CB[8], and SC4AD serves as an efficient light‐harvesting platform. It facilitates cascade energy transfer and chiral transfer to acceptor dyes. Co‐assembly with a PVA matrix produces a multicolor solid film that exhibits enhanced luminescence dissymmetry factors (glum), enabling ...
Yongxue Li   +5 more
wiley   +1 more source

Allosteric DNAzyme‐Enabled Sensitive and Multiplex Detection of Biomarkers for Rapid Diagnosis of Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen   +12 more
wiley   +1 more source

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun   +12 more
wiley   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

open access: yesAdvanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju   +5 more
wiley   +1 more source

Genetic Code Expanded T Cell for Controllable Immunotherapy

open access: yesAdvanced Science, EarlyView.
Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang   +4 more
wiley   +1 more source

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