Results 41 to 50 of about 46,542 (265)

Biosensing with Nanofluidic Diodes [PDF]

open access: yesJournal of the American Chemical Society, 2009
Recently reported nanofluidic diodes with highly nonlinear current-voltage characteristics offer a unique possibility to construct different biosensors. These sensors are based on local changes of the surface charge on walls of single conical nanopores induced by binding of an analyte.
Ivan, Vlassiouk   +2 more
openaire   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Fluorescent Labeling Methods for Brain Structure Research

open access: yesMolecules
The brain is a complex structural network. The employment of fluorescent labeling techniques in conjunction with advanced imaging methodologies facilitates comprehensive analysis of multiscale brain anatomy, thereby offering insights into fundamental ...
Chunguang Yin   +8 more
doaj   +1 more source

The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1

open access: yesCell & Bioscience, 2023
Background Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is evaluated.
Haojie Cheng   +9 more
doaj   +1 more source

Nanomaterials for Biosensing Applications [PDF]

open access: yesNanomaterials, 2016
Nanomaterials have shown tremendous potentials to impact the broad field of biological sensing. Nanomaterials, with extremely small sizes and appropriate surface modifications, allow intimate interaction with target biomolecules. [...]
Hou, Sichao, Zhang, Aiying, Su, Ming
openaire   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi   +4 more
wiley   +1 more source

Electroreductive amination of carboxylic acids by cobalt catalysis

open access: yesNature Communications
Catalytic reduction of carboxylic acids to valuable chemicals is highly desirable yet challenging for both biomass conversion and organic synthesis. Here we describe an efficient and sustainable electrocatalytic hydrogenation of carboxylic acids with ...
Huihua Bi   +4 more
doaj   +1 more source

Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

open access: yesNature Communications, 2020
Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and ...
Xiaoyi Fu   +8 more
doaj   +1 more source

Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1

open access: yesCell Death and Disease, 2023
Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions ...
Huitong Bu   +8 more
doaj   +1 more source

High-Performance Liquid Chromatography–Diode Array Detection Combined with Chemometrics for Simultaneous Quantitative Analysis of Five Active Constituents in a Chinese Medicine Formula Wen-Qing-Yin

open access: yesChemosensors, 2022
In this work, a simple analytical strategy combining high-performance liquid chromatography–diode array detection (HPLC-DAD) and the chemometric method was developed for the simultaneous quantification of 5-hydroxymethyl-2-furfural (HMF), paeoniflorin ...
Jun-Chen Chen   +5 more
doaj   +1 more source

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