Results 41 to 50 of about 46,007 (267)

Glyconanomaterials for biosensing applications [PDF]

Biosensors and Bioelectronics, 2016
Nanomaterials constitute a class of structures that have unique physiochemical properties and are excellent scaffolds for presenting carbohydrates, important biomolecules that mediate a wide variety of important biological events. The fabrication of carbohydrate-presenting nanomaterials, glyconanomaterials, is of high interest and utility, combining ...
Hao, Nanjing, Neranon, Kitjanit, Ramström, Olof, Yan, Mingdi   +3 more
openaire   +3 more sources

Template‐Confined Synthesis of Shape‐Engineered Single‐Crystal Gold Microplates in Lithographically‐Defined Polymeric Patterns

Advanced Functional Materials, EarlyView.
Single‐crystal gold microplates are high‐performance nanomaterials with an impressive wafer‐based application space. Progress has, however, been tempered by an inability to exert synthetic control over microplate size, shape, and positioning. In this work, control over these parameters is demonstrated using a seed‐mediated synthesis that both confines ...
Debasish Panda, Md Rashed Nizam, Walker J. Tuff, Collin C. Wyant, Maksym Zhukovskyi, Matthew R. Rosenberger, Botond Sánta, Edward C. Kinzel, Robert A. Hughes, Svetlana Neretina   +9 more
wiley   +1 more source

General (hetero)polyaryl amine synthesis via multicomponent cycloaromatization of amines

Nature Communications
(Hetero)polyaryl amines are extensively prevalent in pharmaceuticals, fine chemicals, and materials but the intricate and varied nature of their structures severely restricts their synthesis. Here, we present a selective multicomponent cycloaromatization
Lebin Su, Jianyu Dong, Yang Shen, Shimin Xie, Shaofeng Wu, Neng Pan, Feng Liu, Qian Shang, Fangfang Cai, Tian-Bing Ren, Lin Yuan, Shuang-Feng Yin, Li-Biao Han, Yongbo Zhou   +13 more
doaj   +1 more source

Fluorescent Labeling Methods for Brain Structure Research

Molecules
The brain is a complex structural network. The employment of fluorescent labeling techniques in conjunction with advanced imaging methodologies facilitates comprehensive analysis of multiscale brain anatomy, thereby offering insights into fundamental ...
Chunguang Yin, Jiangcan Li, Keyu Meng, Jiade Zhang, Meihe Chen, Ruibing Chen, Yuyang Hu, Shuodong Wang, Sheng Xie   +8 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Electroreductive amination of carboxylic acids by cobalt catalysis

Nature Communications
Catalytic reduction of carboxylic acids to valuable chemicals is highly desirable yet challenging for both biomass conversion and organic synthesis. Here we describe an efficient and sustainable electrocatalytic hydrogenation of carboxylic acids with ...
Huihua Bi, Zhizheng Chen, Changsheng Bi, Shuanglin Qu, Jie Liu   +4 more
doaj   +1 more source

Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

Nature Communications, 2020
Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and ...
Xiaoyi Fu, Guoliang Ke, Fangqi Peng, Xue Hu, Jiaqi Li, Yuyan Shi, Gezhi Kong, Xiao-Bing Zhang, Weihong Tan   +8 more
doaj   +1 more source

Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1

Cell Death and Disease, 2023
Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions ...
Huitong Bu, Xianling Lan, Haojie Cheng, Chaozhu Pei, Min Ouyang, Yan Chen, Xiaoqin Huang, Li Yu, Yongjun Tan   +8 more
doaj   +1 more source

High-Performance Liquid Chromatography–Diode Array Detection Combined with Chemometrics for Simultaneous Quantitative Analysis of Five Active Constituents in a Chinese Medicine Formula Wen-Qing-Yin

Chemosensors, 2022
In this work, a simple analytical strategy combining high-performance liquid chromatography–diode array detection (HPLC-DAD) and the chemometric method was developed for the simultaneous quantification of 5-hydroxymethyl-2-furfural (HMF), paeoniflorin ...
Jun-Chen Chen, Hai-Long Wu, Tong Wang, Ming-Yue Dong, Yue Chen, Ru-Qin Yu   +5 more
doaj   +1 more source

Biosensing with Nanofluidic Diodes [PDF]

Journal of the American Chemical Society, 2009
Recently reported nanofluidic diodes with highly nonlinear current-voltage characteristics offer a unique possibility to construct different biosensors. These sensors are based on local changes of the surface charge on walls of single conical nanopores induced by binding of an analyte.
Ivan, Vlassiouk, Thomas R, Kozel, Zuzanna S, Siwy   +2 more
openaire   +2 more sources