Results 71 to 80 of about 79,187 (302)

Second-order calibration applied to quantification of two active components of Schisandra chinensis in complex matrix

Journal of Pharmaceutical Analysis, 2012
The effectiveness of traditional Chinese medicine (TCM) against various diseases urges more low cost, speed and sensitive analytical methods for investigating the phamacology of TCM and providing a theoretical basis for clinical use.
Xiao-Hua Zhang, Hai-Long Wu, Jian-Yao Wang, Yao Chen, Yong-Jie Yu, Chong-Chong Nie, Chao Kang, De-Zhu Tu, Ru-Qin Yu   +8 more
doaj   +1 more source

Self-Powered All-in-One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps. [PDF]

Adv Sci (Weinh)
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Kim JS, Kang TW, Yoo H, Ha J, Huang Y, Han H, Ahn CW, Yeo WH, Oh IK.   +8 more
europepmc   +2 more sources

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

Electroreductive amination of carboxylic acids by cobalt catalysis

Nature Communications
Catalytic reduction of carboxylic acids to valuable chemicals is highly desirable yet challenging for both biomass conversion and organic synthesis. Here we describe an efficient and sustainable electrocatalytic hydrogenation of carboxylic acids with ...
Huihua Bi, Zhizheng Chen, Changsheng Bi, Shuanglin Qu, Jie Liu   +4 more
doaj   +1 more source

Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1

Cell Death and Disease, 2023
Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions ...
Huitong Bu, Xianling Lan, Haojie Cheng, Chaozhu Pei, Min Ouyang, Yan Chen, Xiaoqin Huang, Li Yu, Yongjun Tan   +8 more
doaj   +1 more source

High-Performance Liquid Chromatography–Diode Array Detection Combined with Chemometrics for Simultaneous Quantitative Analysis of Five Active Constituents in a Chinese Medicine Formula Wen-Qing-Yin

Chemosensors, 2022
In this work, a simple analytical strategy combining high-performance liquid chromatography–diode array detection (HPLC-DAD) and the chemometric method was developed for the simultaneous quantification of 5-hydroxymethyl-2-furfural (HMF), paeoniflorin ...
Jun-Chen Chen, Hai-Long Wu, Tong Wang, Ming-Yue Dong, Yue Chen, Ru-Qin Yu   +5 more
doaj   +1 more source

Hydrogel microparticles for biosensing [PDF]

European Polymer Journal, 2015
Due to their hydrophilic, biocompatible, and highly tunable nature, hydrogel materials have attracted strong interest in the recent years for numerous biotechnological applications. In particular, their solution-like environment and non-fouling nature in complex biological samples render hydrogels as ideal substrates for biosensing applications ...
Hill, W. Adam, Le Goff, Gaelle, Srinivas, Rathi L., Doyle, Patrick S   +3 more
openaire   +4 more sources

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Protein biomarker enrichment by biomarker antibody complex elution for immunoassay biosensing

, 2011
It is very challenging to perform sample enrichment for protein biomarkers because proteins can easily change conformation and denature. In this paper we demonstrate protein enrichment suited for high-sensitivity integrated immuno-biosensing.
Feitsma, H., Gwenola Sabatte, Prins, M.W.J., Menno W.J. Prins, Evers, T.H., Sabatté, G.S., Toon H. Evers, Harma Feitsma   +7 more
core   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source