Results 81 to 90 of about 201,023 (316)
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Succinate dehydrogenase (SDH) is a key fungicidal target, but rational inhibitors design has been impeded by the lack of fungal SDH structure. Here, we show the cryo-EM structure of SDH from Saccharomyces cerevisiae (ScSDH) in apo (3.36 Å) and ubiquinone-
Zhi-Wen Li +13 more
doaj +1 more source
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi +7 more
wiley +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
A Novel Electronic Nose Using Biomimetic Spiking Neural Network for Mixed Gas Recognition
Odors existing in natural environment are typically mixtures of a large variety of chemical compounds in specific proportions. It is a challenging task for an electronic nose to recognize the gas mixtures.
Yingying Xue +6 more
doaj +1 more source
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang +13 more
wiley +1 more source
The accuracy of a point-of-care whole blood glucose sensor can be considerably influenced by hematocrit; therefore, an on-chip Hct correction protocol was developed and incorporated to meet the clinical demands.
Chih-Wei Weng +3 more
doaj +1 more source
Recent Advances in Biosensor Technology for Potential Applications – An Overview
Imperative utilization of biosensors has acquired paramount importance in the field of drug discovery, biomedicine, food safety standards, defense, security, and environmental monitoring.
S. Vigneshvar +3 more
semanticscholar +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Application of Sensing Devices in the Detection of Oral, Pulmonary, and Gastrointestinal Diseases
Biomedical sensing technology is developing at a tremendous pace and is expected to become an effective clinical tool for the diagnosis and monitoring of human health.
Weijie Yu +8 more
doaj +1 more source

